MotifNFIC.H12INVIVO.1.PSM.A
Gene (human)NFIC
(GeneCards)
Gene synonyms (human)NFI
Gene (mouse)Nfic
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length9
ConsensusvWGCCARvh
GC content57.51%
Information content (bits; total / per base)9.456 / 1.051
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words991

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (41) 0.818 0.869 0.674 0.749 0.72 0.764 1.79 2.006 98.409 451.032
Mouse 2 (6) 0.762 0.791 0.614 0.643 0.641 0.664 1.579 1.617 5.921 14.387

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.98 0.964 0.971 0.952 0.96 0.937
best 0.982 0.969 0.976 0.96 0.967 0.947
Methyl HT-SELEX, 1 experiments median 0.982 0.969 0.976 0.96 0.967 0.947
best 0.982 0.969 0.976 0.96 0.967 0.947
Non-Methyl HT-SELEX, 1 experiments median 0.978 0.959 0.967 0.945 0.954 0.928
best 0.978 0.959 0.967 0.945 0.954 0.928

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 3.957 10.844 0.134 0.058

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.853 0.451 0.835 0.545
batch 2 0.824 0.556 0.862 0.669
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classSMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF familyNF-1 {7.1.2} (TFClass)
TF subfamily {7.1.2.0} (TFClass)
TFClass IDTFClass: 7.1.2.0.3
HGNCHGNC:7786
MGIMGI:109591
EntrezGene (human)GeneID:4782
(SSTAR profile)
EntrezGene (mouse)GeneID:18029
(SSTAR profile)
UniProt ID (human)NFIC_HUMAN
UniProt ID (mouse)NFIC_MOUSE
UniProt AC (human)P08651
(TFClass)
UniProt AC (mouse)P70255
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 2 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01148.0257.0445.0141.0
02222.09.0104.0656.0
032.013.0958.018.0
048.0973.06.04.0
054.0978.01.08.0
06965.012.02.012.0
07572.08.0405.06.0
08250.0210.0465.066.0
09386.0147.0136.0322.0
PFM
ACGT
010.1490.2590.4490.142
020.2240.0090.1050.662
030.0020.0130.9670.018
040.0080.9820.0060.004
050.0040.9870.0010.008
060.9740.0120.0020.012
070.5770.0080.4090.006
080.2520.2120.4690.067
090.390.1480.1370.325
PWM
ACGT
01-0.5110.0360.583-0.558
02-0.109-3.147-0.8590.969
03-4.204-2.831.347-2.537
04-3.2451.363-3.475-3.775
05-3.7751.368-4.517-3.245
061.355-2.9-4.204-2.9
070.833-3.2450.489-3.475
080.009-0.1640.626-1.304
090.441-0.517-0.5940.261
Standard thresholds
P-value Threshold
0.001 5.00763
0.0005 6.16921
0.0001 7.545925