MotifNFIC.H12INVIVO.0.PSM.A
Gene (human)NFIC
(GeneCards)
Gene synonyms (human)NFI
Gene (mouse)Nfic
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length17
ConsensusbYTGGCWnnnnbCCMdv
GC content58.52%
Information content (bits; total / per base)12.338 / 0.726
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (41) 0.887 0.984 0.827 0.974 0.847 0.975 3.287 5.583 204.538 856.0
Mouse 2 (6) 0.802 0.863 0.724 0.809 0.722 0.802 2.507 2.889 8.004 36.143

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 1.0 0.999 0.999 0.999 0.998 0.997
best 1.0 0.999 1.0 0.999 0.999 0.999
Methyl HT-SELEX, 1 experiments median 1.0 0.999 1.0 0.999 0.999 0.999
best 1.0 0.999 1.0 0.999 0.999 0.999
Non-Methyl HT-SELEX, 1 experiments median 0.999 0.999 0.999 0.998 0.997 0.996
best 0.999 0.999 0.999 0.998 0.997 0.996

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 6.066 15.925 0.159 0.054

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.928 0.766 0.899 0.582
batch 2 0.871 0.685 0.861 0.656
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classSMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF familyNF-1 {7.1.2} (TFClass)
TF subfamily {7.1.2.0} (TFClass)
TFClass IDTFClass: 7.1.2.0.3
HGNCHGNC:7786
MGIMGI:109591
EntrezGene (human)GeneID:4782
(SSTAR profile)
EntrezGene (mouse)GeneID:18029
(SSTAR profile)
UniProt ID (human)NFIC_HUMAN
UniProt ID (mouse)NFIC_MOUSE
UniProt AC (human)P08651
(TFClass)
UniProt AC (mouse)P70255
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 2 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
0192.0420.0194.0294.0
0222.0458.022.0498.0
036.03.018.0973.0
041.00.0995.04.0
059.06.0981.04.0
0695.0892.011.02.0
07532.0169.010.0289.0
08183.0304.0349.0164.0
09281.0339.0202.0178.0
10301.0270.0278.0151.0
11313.0150.0239.0298.0
1264.0132.0441.0363.0
1361.0808.028.0103.0
1467.0877.016.040.0
15541.0349.026.084.0
16525.053.0274.0148.0
17221.0184.0450.0145.0
PFM
ACGT
010.0920.420.1940.294
020.0220.4580.0220.498
030.0060.0030.0180.973
040.0010.00.9950.004
050.0090.0060.9810.004
060.0950.8920.0110.002
070.5320.1690.010.289
080.1830.3040.3490.164
090.2810.3390.2020.178
100.3010.270.2780.151
110.3130.150.2390.298
120.0640.1320.4410.363
130.0610.8080.0280.103
140.0670.8770.0160.04
150.5410.3490.0260.084
160.5250.0530.2740.148
170.2210.1840.450.145
PWM
ACGT
01-0.9880.516-0.2520.161
02-2.3620.602-2.3620.686
03-3.484-3.975-2.5461.354
04-4.525-4.9821.376-3.783
05-3.156-3.4841.362-3.783
06-0.9561.267-2.985-4.213
070.752-0.388-3.0660.144
08-0.3090.1940.332-0.418
090.1160.303-0.212-0.337
100.1840.0760.105-0.5
110.223-0.506-0.0450.175
12-1.343-0.6330.5650.371
13-1.391.168-2.136-0.877
14-1.2981.25-2.653-1.797
150.7680.332-2.206-1.077
160.738-1.5260.091-0.52
17-0.122-0.3040.585-0.54
Standard thresholds
P-value Threshold
0.001 3.98891
0.0005 5.05391
0.0001 7.20966