MotifNFIC.H12CORE.0.PSM.A
Gene (human)NFIC
(GeneCards)
Gene synonyms (human)NFI
Gene (mouse)Nfic
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length17
ConsensusnYTGGCdnCdhGCCARn
GC content55.44%
Information content (bits; total / per base)17.698 / 1.041
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words2386

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 6 (41) 0.867 0.981 0.81 0.977 0.822 0.976 2.944 6.295 208.097 883.921
Mouse 2 (6) 0.765 0.839 0.698 0.766 0.7 0.781 2.412 2.639 8.921 32.658

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 1.0 1.0 1.0 1.0 0.999 0.999
best 1.0 1.0 1.0 1.0 1.0 1.0
Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 1.0 1.0 1.0
best 1.0 1.0 1.0 1.0 1.0 1.0
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 1.0 0.999 0.998 0.998
best 1.0 1.0 1.0 0.999 0.998 0.998

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 5.569 15.17 0.168 0.066

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.985 0.94 0.965 0.638
batch 2 0.886 0.689 0.876 0.738
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classSMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF familyNF-1 {7.1.2} (TFClass)
TF subfamily {7.1.2.0} (TFClass)
TFClass IDTFClass: 7.1.2.0.3
HGNCHGNC:7786
MGIMGI:109591
EntrezGene (human)GeneID:4782
(SSTAR profile)
EntrezGene (mouse)GeneID:18029
(SSTAR profile)
UniProt ID (human)NFIC_HUMAN
UniProt ID (mouse)NFIC_MOUSE
UniProt AC (human)P08651
(TFClass)
UniProt AC (mouse)P70255
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 6 human, 2 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01484.25762.25632.25507.25
02104.0481.042.01759.0
0320.013.017.02336.0
0416.018.02343.09.0
0520.020.02333.013.0
06191.02156.013.026.0
071315.0138.0565.0368.0
08737.0584.0324.0741.0
090.01322.00.01064.0
10629.0281.0882.0594.0
11347.0547.0230.01262.0
1212.012.02175.0187.0
138.02346.018.014.0
1411.02343.012.020.0
152330.030.010.016.0
161790.7554.75464.7575.75
17583.75591.75727.75482.75
PFM
ACGT
010.2030.3190.2650.213
020.0440.2020.0180.737
030.0080.0050.0070.979
040.0070.0080.9820.004
050.0080.0080.9780.005
060.080.9040.0050.011
070.5510.0580.2370.154
080.3090.2450.1360.311
090.00.5540.00.446
100.2640.1180.370.249
110.1450.2290.0960.529
120.0050.0050.9120.078
130.0030.9830.0080.006
140.0050.9820.0050.008
150.9770.0130.0040.007
160.7510.0230.1950.032
170.2450.2480.3050.202
PWM
ACGT
01-0.2080.2440.058-0.162
02-1.731-0.214-2.6111.079
03-3.306-3.69-3.4531.363
04-3.507-3.4011.366-4.002
05-3.306-3.3061.361-3.69
06-1.1321.283-3.69-3.064
070.789-1.453-0.054-0.481
080.211-0.021-0.6080.216
09-5.7290.794-5.7290.577
100.053-0.7490.39-0.004
11-0.539-0.086-0.9480.748
12-3.759-3.7591.291-1.153
13-4.0971.367-3.401-3.625
14-3.8341.366-3.759-3.306
151.36-2.93-3.914-3.507
161.097-2.357-0.249-2.042
17-0.022-0.0080.198-0.211
Standard thresholds
P-value Threshold
0.001 0.79231
0.0005 2.24871
0.0001 5.27686