| Motif | NFIC.H12CORE.0.PSM.A |
| Gene (human) | NFIC (GeneCards) |
| Gene synonyms (human) | NFI |
| Gene (mouse) | Nfic |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | NFIC.H12CORE.0.PSM.A |
| Gene (human) | NFIC (GeneCards) |
| Gene synonyms (human) | NFI |
| Gene (mouse) | Nfic |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 17 |
| Consensus | nYTGGCdnCdhGCCARn |
| GC content | 55.44% |
| Information content (bits; total / per base) | 17.698 / 1.041 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2386 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 6 (41) | 0.867 | 0.981 | 0.81 | 0.977 | 0.822 | 0.976 | 2.944 | 6.295 | 208.097 | 883.921 |
| Mouse | 2 (6) | 0.765 | 0.839 | 0.698 | 0.766 | 0.7 | 0.781 | 2.412 | 2.639 | 8.921 | 32.658 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Non-Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 5.569 | 15.17 | 0.168 | 0.066 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.985 | 0.94 | 0.965 | 0.638 |
| batch 2 | 0.886 | 0.689 | 0.876 | 0.738 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | NF-1 {7.1.2} (TFClass) |
| TF subfamily | {7.1.2.0} (TFClass) |
| TFClass ID | TFClass: 7.1.2.0.3 |
| HGNC | HGNC:7786 |
| MGI | MGI:109591 |
| EntrezGene (human) | GeneID:4782 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18029 (SSTAR profile) |
| UniProt ID (human) | NFIC_HUMAN |
| UniProt ID (mouse) | NFIC_MOUSE |
| UniProt AC (human) | P08651 (TFClass) |
| UniProt AC (mouse) | P70255 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 6 human, 2 mouse |
| HT-SELEX | 1 |
| Methyl-HT-SELEX | 1 |
| PCM | NFIC.H12CORE.0.PSM.A.pcm |
| PWM | NFIC.H12CORE.0.PSM.A.pwm |
| PFM | NFIC.H12CORE.0.PSM.A.pfm |
| Alignment | NFIC.H12CORE.0.PSM.A.words.tsv |
| Threshold to P-value map | NFIC.H12CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | NFIC.H12CORE.0.PSM.A_jaspar_format.txt |
| MEME format | NFIC.H12CORE.0.PSM.A_meme_format.meme |
| Transfac format | NFIC.H12CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 484.25 | 762.25 | 632.25 | 507.25 |
| 02 | 104.0 | 481.0 | 42.0 | 1759.0 |
| 03 | 20.0 | 13.0 | 17.0 | 2336.0 |
| 04 | 16.0 | 18.0 | 2343.0 | 9.0 |
| 05 | 20.0 | 20.0 | 2333.0 | 13.0 |
| 06 | 191.0 | 2156.0 | 13.0 | 26.0 |
| 07 | 1315.0 | 138.0 | 565.0 | 368.0 |
| 08 | 737.0 | 584.0 | 324.0 | 741.0 |
| 09 | 0.0 | 1322.0 | 0.0 | 1064.0 |
| 10 | 629.0 | 281.0 | 882.0 | 594.0 |
| 11 | 347.0 | 547.0 | 230.0 | 1262.0 |
| 12 | 12.0 | 12.0 | 2175.0 | 187.0 |
| 13 | 8.0 | 2346.0 | 18.0 | 14.0 |
| 14 | 11.0 | 2343.0 | 12.0 | 20.0 |
| 15 | 2330.0 | 30.0 | 10.0 | 16.0 |
| 16 | 1790.75 | 54.75 | 464.75 | 75.75 |
| 17 | 583.75 | 591.75 | 727.75 | 482.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.203 | 0.319 | 0.265 | 0.213 |
| 02 | 0.044 | 0.202 | 0.018 | 0.737 |
| 03 | 0.008 | 0.005 | 0.007 | 0.979 |
| 04 | 0.007 | 0.008 | 0.982 | 0.004 |
| 05 | 0.008 | 0.008 | 0.978 | 0.005 |
| 06 | 0.08 | 0.904 | 0.005 | 0.011 |
| 07 | 0.551 | 0.058 | 0.237 | 0.154 |
| 08 | 0.309 | 0.245 | 0.136 | 0.311 |
| 09 | 0.0 | 0.554 | 0.0 | 0.446 |
| 10 | 0.264 | 0.118 | 0.37 | 0.249 |
| 11 | 0.145 | 0.229 | 0.096 | 0.529 |
| 12 | 0.005 | 0.005 | 0.912 | 0.078 |
| 13 | 0.003 | 0.983 | 0.008 | 0.006 |
| 14 | 0.005 | 0.982 | 0.005 | 0.008 |
| 15 | 0.977 | 0.013 | 0.004 | 0.007 |
| 16 | 0.751 | 0.023 | 0.195 | 0.032 |
| 17 | 0.245 | 0.248 | 0.305 | 0.202 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.208 | 0.244 | 0.058 | -0.162 |
| 02 | -1.731 | -0.214 | -2.611 | 1.079 |
| 03 | -3.306 | -3.69 | -3.453 | 1.363 |
| 04 | -3.507 | -3.401 | 1.366 | -4.002 |
| 05 | -3.306 | -3.306 | 1.361 | -3.69 |
| 06 | -1.132 | 1.283 | -3.69 | -3.064 |
| 07 | 0.789 | -1.453 | -0.054 | -0.481 |
| 08 | 0.211 | -0.021 | -0.608 | 0.216 |
| 09 | -5.729 | 0.794 | -5.729 | 0.577 |
| 10 | 0.053 | -0.749 | 0.39 | -0.004 |
| 11 | -0.539 | -0.086 | -0.948 | 0.748 |
| 12 | -3.759 | -3.759 | 1.291 | -1.153 |
| 13 | -4.097 | 1.367 | -3.401 | -3.625 |
| 14 | -3.834 | 1.366 | -3.759 | -3.306 |
| 15 | 1.36 | -2.93 | -3.914 | -3.507 |
| 16 | 1.097 | -2.357 | -0.249 | -2.042 |
| 17 | -0.022 | -0.008 | 0.198 | -0.211 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.79231 |
| 0.0005 | 2.24871 |
| 0.0001 | 5.27686 |