NFIB.H12CORE.1.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFIB.H12CORE.1.PS.A
Gene (human)	NFIB (GeneCards)
Gene synonyms (human)
Gene (mouse)	Nfib
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	9
Consensus	nWGCCARvh
GC content	55.95%
Information content (bits; total / per base)	9.445 / 1.049
Data sources	ChIP-Seq + HT-SELEX
Aligned words	992

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.893	0.93	0.813	0.846	0.792	0.831	2.21	2.331	446.515	684.42
Mouse	4 (28)	0.836	0.892	0.691	0.784	0.73	0.79	1.784	2.078	71.577	143.081

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.852	0.832	0.794	0.785	0.762	0.757
Overall, 4 experiments	best	0.987	0.978	0.982	0.97	0.973	0.958
Methyl HT-SELEX, 1 experiments	median	0.987	0.978	0.982	0.97	0.973	0.958
Methyl HT-SELEX, 1 experiments	best	0.987	0.978	0.982	0.97	0.973	0.958
Non-Methyl HT-SELEX, 3 experiments	median	0.722	0.694	0.61	0.609	0.557	0.566
Non-Methyl HT-SELEX, 3 experiments	best	0.983	0.97	0.977	0.961	0.967	0.948

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.73	0.128	0.142	0.0

TF superclass	beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF class	SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF family	NF-1 {7.1.2} (TFClass)
TF subfamily	{7.1.2.0} (TFClass)
TFClass ID	TFClass: 7.1.2.0.2
HGNC	HGNC:7785
MGI	MGI:103188
EntrezGene (human)	GeneID:4781 (SSTAR profile)
EntrezGene (mouse)	GeneID:18028 (SSTAR profile)
UniProt ID (human)	NFIB_HUMAN
UniProt ID (mouse)	NFIB_MOUSE
UniProt AC (human)	O00712 (TFClass)
UniProt AC (mouse)	P97863 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 4 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	NFIB.H12CORE.1.PS.A.pcm
PWM	NFIB.H12CORE.1.PS.A.pwm
PFM	NFIB.H12CORE.1.PS.A.pfm
Alignment	NFIB.H12CORE.1.PS.A.words.tsv
Threshold to P-value map	NFIB.H12CORE.1.PS.A.thr
Motif in other formats
JASPAR format	NFIB.H12CORE.1.PS.A_jaspar_format.txt
MEME format	NFIB.H12CORE.1.PS.A_meme_format.meme
Transfac format	NFIB.H12CORE.1.PS.A_transfac_format.txt
Homer format	NFIB.H12CORE.1.PS.A_homer_format_0.001.txt NFIB.H12CORE.1.PS.A_homer_format_0.0005.txt NFIB.H12CORE.1.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	193.0	193.0	483.0	123.0
02	233.0	8.0	71.0	680.0
03	5.0	14.0	952.0	21.0
04	12.0	967.0	2.0	11.0
05	11.0	973.0	1.0	7.0
06	961.0	21.0	1.0	9.0
07	615.0	3.0	364.0	10.0
08	249.0	156.0	490.0	97.0
09	359.0	183.0	113.0	337.0

PFM

	A	C	G	T
01	0.195	0.195	0.487	0.124
02	0.235	0.008	0.072	0.685
03	0.005	0.014	0.96	0.021
04	0.012	0.975	0.002	0.011
05	0.011	0.981	0.001	0.007
06	0.969	0.021	0.001	0.009
07	0.62	0.003	0.367	0.01
08	0.251	0.157	0.494	0.098
09	0.362	0.184	0.114	0.34

PWM

	A	C	G	T
01	-0.249	-0.249	0.663	-0.694
02	-0.062	-3.246	-1.234	1.004
03	-3.615	-2.765	1.34	-2.397
04	-2.901	1.356	-4.205	-2.977
05	-2.977	1.362	-4.518	-3.354
06	1.349	-2.397	-4.518	-3.148
07	0.904	-3.968	0.382	-3.059
08	0.004	-0.46	0.678	-0.928
09	0.368	-0.301	-0.778	0.305

Standard thresholds

P-value	Threshold
0.001	4.893
0.0005	6.106985
0.0001	7.44521