| Motif | NFIB.H12CORE.0.PSM.A |
| Gene (human) | NFIB (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfib |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | NFIB.H12CORE.0.PSM.A |
| Gene (human) | NFIB (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfib |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 20 |
| Consensus | dnYTGGCWnMdWGCCAAnnn |
| GC content | 53.88% |
| Information content (bits; total / per base) | 20.621 / 1.031 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2452 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (14) | 0.976 | 0.997 | 0.973 | 0.996 | 0.972 | 0.998 | 7.058 | 7.688 | 827.702 | 1257.495 |
| Mouse | 4 (28) | 0.836 | 0.972 | 0.766 | 0.961 | 0.793 | 0.964 | 2.869 | 5.452 | 136.53 | 403.161 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.87 | 0.88 | 0.804 | 0.817 | 0.776 | 0.788 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.739 | 0.761 | 0.608 | 0.634 | 0.553 | 0.576 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.66 | 0.088 | -0.186 | -0.147 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | NF-1 {7.1.2} (TFClass) |
| TF subfamily | {7.1.2.0} (TFClass) |
| TFClass ID | TFClass: 7.1.2.0.2 |
| HGNC | HGNC:7785 |
| MGI | MGI:103188 |
| EntrezGene (human) | GeneID:4781 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18028 (SSTAR profile) |
| UniProt ID (human) | NFIB_HUMAN |
| UniProt ID (mouse) | NFIB_MOUSE |
| UniProt AC (human) | O00712 (TFClass) |
| UniProt AC (mouse) | P97863 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 4 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | NFIB.H12CORE.0.PSM.A.pcm |
| PWM | NFIB.H12CORE.0.PSM.A.pwm |
| PFM | NFIB.H12CORE.0.PSM.A.pfm |
| Alignment | NFIB.H12CORE.0.PSM.A.words.tsv |
| Threshold to P-value map | NFIB.H12CORE.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | NFIB.H12CORE.0.PSM.A_jaspar_format.txt |
| MEME format | NFIB.H12CORE.0.PSM.A_meme_format.meme |
| Transfac format | NFIB.H12CORE.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1014.5 | 394.5 | 484.5 | 558.5 |
| 02 | 529.0 | 708.0 | 674.0 | 541.0 |
| 03 | 60.0 | 588.0 | 36.0 | 1768.0 |
| 04 | 1.0 | 0.0 | 8.0 | 2443.0 |
| 05 | 0.0 | 1.0 | 2451.0 | 0.0 |
| 06 | 0.0 | 9.0 | 2442.0 | 1.0 |
| 07 | 65.0 | 2376.0 | 8.0 | 3.0 |
| 08 | 1872.0 | 99.0 | 205.0 | 276.0 |
| 09 | 621.0 | 916.0 | 367.0 | 548.0 |
| 10 | 1121.0 | 1313.0 | 10.0 | 8.0 |
| 11 | 437.0 | 403.0 | 1111.0 | 501.0 |
| 12 | 338.0 | 300.0 | 27.0 | 1787.0 |
| 13 | 1.0 | 1.0 | 2428.0 | 22.0 |
| 14 | 0.0 | 2444.0 | 8.0 | 0.0 |
| 15 | 0.0 | 2452.0 | 0.0 | 0.0 |
| 16 | 2442.0 | 10.0 | 0.0 | 0.0 |
| 17 | 1813.0 | 31.0 | 585.0 | 23.0 |
| 18 | 658.0 | 764.0 | 581.0 | 449.0 |
| 19 | 644.25 | 564.25 | 392.25 | 851.25 |
| 20 | 524.0 | 821.0 | 408.0 | 699.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.414 | 0.161 | 0.198 | 0.228 |
| 02 | 0.216 | 0.289 | 0.275 | 0.221 |
| 03 | 0.024 | 0.24 | 0.015 | 0.721 |
| 04 | 0.0 | 0.0 | 0.003 | 0.996 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.004 | 0.996 | 0.0 |
| 07 | 0.027 | 0.969 | 0.003 | 0.001 |
| 08 | 0.763 | 0.04 | 0.084 | 0.113 |
| 09 | 0.253 | 0.374 | 0.15 | 0.223 |
| 10 | 0.457 | 0.535 | 0.004 | 0.003 |
| 11 | 0.178 | 0.164 | 0.453 | 0.204 |
| 12 | 0.138 | 0.122 | 0.011 | 0.729 |
| 13 | 0.0 | 0.0 | 0.99 | 0.009 |
| 14 | 0.0 | 0.997 | 0.003 | 0.0 |
| 15 | 0.0 | 1.0 | 0.0 | 0.0 |
| 16 | 0.996 | 0.004 | 0.0 | 0.0 |
| 17 | 0.739 | 0.013 | 0.239 | 0.009 |
| 18 | 0.268 | 0.312 | 0.237 | 0.183 |
| 19 | 0.263 | 0.23 | 0.16 | 0.347 |
| 20 | 0.214 | 0.335 | 0.166 | 0.285 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.503 | -0.439 | -0.234 | -0.093 |
| 02 | -0.147 | 0.144 | 0.095 | -0.125 |
| 03 | -2.295 | -0.042 | -2.785 | 1.057 |
| 04 | -5.339 | -5.753 | -4.124 | 1.38 |
| 05 | -5.753 | -5.339 | 1.384 | -5.753 |
| 06 | -5.753 | -4.028 | 1.38 | -5.339 |
| 07 | -2.218 | 1.352 | -4.124 | -4.822 |
| 08 | 1.114 | -1.807 | -1.089 | -0.794 |
| 09 | 0.013 | 0.401 | -0.511 | -0.112 |
| 10 | 0.602 | 0.76 | -3.941 | -4.124 |
| 11 | -0.337 | -0.418 | 0.593 | -0.201 |
| 12 | -0.593 | -0.711 | -3.056 | 1.068 |
| 13 | -5.339 | -5.339 | 1.374 | -3.246 |
| 14 | -5.753 | 1.381 | -4.124 | -5.753 |
| 15 | -5.753 | 1.384 | -5.753 | -5.753 |
| 16 | 1.38 | -3.941 | -5.753 | -5.753 |
| 17 | 1.082 | -2.927 | -0.047 | -3.205 |
| 18 | 0.071 | 0.22 | -0.053 | -0.31 |
| 19 | 0.05 | -0.083 | -0.445 | 0.327 |
| 20 | -0.156 | 0.291 | -0.406 | 0.131 |
| P-value | Threshold |
|---|---|
| 0.001 | -3.31089 |
| 0.0005 | -1.39094 |
| 0.0001 | 2.61321 |