MotifNFIA.H12INVITRO.1.PS.A
Gene (human)NFIA
(GeneCards)
Gene synonyms (human)KIAA1439
Gene (mouse)Nfia
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length20
ConsensusnnTTGGCACGdTGCCAAvdn
GC content53.52%
Information content (bits; total / per base)26.384 / 1.319
Data sourcesChIP-Seq + HT-SELEX
Aligned words361

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.527 0.566 0.403 0.481 0.864 0.906 3.189 3.902 279.854 398.886
Mouse 6 (28) 0.503 0.509 0.343 0.358 0.635 0.68 1.572 1.83 17.422 38.824

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 1.0 1.0 0.988 0.989 0.835 0.864
best 1 1 1.0 1.0 0.898 0.916

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 100.0 4.471 0.277 0.181
TF superclassbeta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass)
TF classSMAD/NF-1 DNA-binding domain factors {7.1} (TFClass)
TF familyNF-1 {7.1.2} (TFClass)
TF subfamily {7.1.2.0} (TFClass)
TFClass IDTFClass: 7.1.2.0.1
HGNCHGNC:7784
MGIMGI:108056
EntrezGene (human)GeneID:4774
(SSTAR profile)
EntrezGene (mouse)GeneID:18027
(SSTAR profile)
UniProt ID (human)NFIA_HUMAN
UniProt ID (mouse)NFIA_MOUSE
UniProt AC (human)Q12857
(TFClass)
UniProt AC (mouse)Q02780
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 6 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01123.7587.7552.7596.75
0256.0133.0100.072.0
030.030.00.0331.0
040.00.00.0361.0
050.00.0361.00.0
060.00.0361.00.0
070.0361.00.00.0
08361.00.00.00.0
095.0342.011.03.0
100.00.0229.0132.0
11134.032.0146.049.0
1211.09.00.0341.0
130.00.0361.00.0
140.0361.00.00.0
150.0361.00.00.0
16361.00.00.00.0
17350.00.011.00.0
1878.079.0153.051.0
1995.2538.2576.25151.25
2071.083.085.0122.0
PFM
ACGT
010.3430.2430.1460.268
020.1550.3680.2770.199
030.00.0830.00.917
040.00.00.01.0
050.00.01.00.0
060.00.01.00.0
070.01.00.00.0
081.00.00.00.0
090.0140.9470.030.008
100.00.00.6340.366
110.3710.0890.4040.136
120.030.0250.00.945
130.00.01.00.0
140.01.00.00.0
150.01.00.00.0
161.00.00.00.0
170.970.00.030.0
180.2160.2190.4240.141
190.2640.1060.2110.419
200.1970.230.2350.338
PWM
ACGT
010.311-0.028-0.5260.068
02-0.4670.3830.101-0.222
03-4.132-1.07-4.1321.288
04-4.132-4.132-4.1321.374
05-4.132-4.1321.374-4.132
06-4.132-4.1321.374-4.132
07-4.1321.374-4.132-4.132
081.374-4.132-4.132-4.132
09-2.6511.32-1.995-3.021
10-4.132-4.1320.9210.375
110.39-1.0080.475-0.597
12-1.995-2.17-4.1321.317
13-4.132-4.1321.374-4.132
14-4.1321.374-4.132-4.132
15-4.1321.374-4.132-4.132
161.374-4.132-4.132-4.132
171.343-4.132-1.995-4.132
18-0.143-0.1310.521-0.558
190.053-0.837-0.1660.51
20-0.236-0.082-0.0590.297
Standard thresholds
P-value Threshold
0.001 -5.82204
0.0005 -3.79864
0.0001 0.18151