| Motif | NFE2.H12INVIVO.1.SM.B |
| Gene (human) | NFE2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfe2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | NFE2.H12INVIVO.1.SM.B |
| Gene (human) | NFE2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfe2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 19 |
| Consensus | nnRTGASTCATbvYdRnbn |
| GC content | 44.07% |
| Information content (bits; total / per base) | 16.372 / 0.862 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 2495 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (34) | 0.823 | 0.918 | 0.755 | 0.856 | 0.777 | 0.896 | 2.86 | 3.5 | 345.219 | 668.569 |
| Mouse | 4 (26) | 0.902 | 0.944 | 0.834 | 0.896 | 0.866 | 0.923 | 3.261 | 3.927 | 277.0 | 524.284 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.764 | 0.782 | 0.749 | 0.762 | 0.746 | 0.754 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.998 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.998 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.528 | 0.564 | 0.498 | 0.524 | 0.493 | 0.51 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.562 | 1.849 | 0.15 | 0.192 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.739 | 0.566 | 0.73 | 0.525 |
| batch 2 | 0.78 | 0.507 | 0.758 | 0.491 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | Jun-related {1.1.1} (TFClass) |
| TF subfamily | NFE2 {1.1.1.2} (TFClass) |
| TFClass ID | TFClass: 1.1.1.2.1 |
| HGNC | HGNC:7780 |
| MGI | MGI:97308 |
| EntrezGene (human) | GeneID:4778 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18022 (SSTAR profile) |
| UniProt ID (human) | NFE2_HUMAN |
| UniProt ID (mouse) | NFE2_MOUSE |
| UniProt AC (human) | Q16621 (TFClass) |
| UniProt AC (mouse) | Q07279 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 4 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | NFE2.H12INVIVO.1.SM.B.pcm |
| PWM | NFE2.H12INVIVO.1.SM.B.pwm |
| PFM | NFE2.H12INVIVO.1.SM.B.pfm |
| Alignment | NFE2.H12INVIVO.1.SM.B.words.tsv |
| Threshold to P-value map | NFE2.H12INVIVO.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NFE2.H12INVIVO.1.SM.B_jaspar_format.txt |
| MEME format | NFE2.H12INVIVO.1.SM.B_meme_format.meme |
| Transfac format | NFE2.H12INVIVO.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 446.25 | 581.25 | 794.25 | 673.25 |
| 02 | 761.75 | 829.75 | 581.75 | 321.75 |
| 03 | 1826.0 | 81.0 | 558.0 | 30.0 |
| 04 | 11.0 | 45.0 | 6.0 | 2433.0 |
| 05 | 8.0 | 4.0 | 2389.0 | 94.0 |
| 06 | 2471.0 | 20.0 | 3.0 | 1.0 |
| 07 | 7.0 | 1166.0 | 1304.0 | 18.0 |
| 08 | 3.0 | 2.0 | 7.0 | 2483.0 |
| 09 | 84.0 | 2408.0 | 1.0 | 2.0 |
| 10 | 2480.0 | 1.0 | 13.0 | 1.0 |
| 11 | 2.0 | 375.0 | 67.0 | 2051.0 |
| 12 | 242.0 | 793.0 | 1062.0 | 398.0 |
| 13 | 1296.0 | 571.0 | 551.0 | 77.0 |
| 14 | 180.0 | 450.0 | 200.0 | 1665.0 |
| 15 | 274.0 | 262.0 | 1211.0 | 748.0 |
| 16 | 1521.0 | 329.0 | 363.0 | 282.0 |
| 17 | 435.0 | 863.0 | 682.0 | 515.0 |
| 18 | 409.75 | 475.75 | 544.75 | 1064.75 |
| 19 | 688.0 | 796.0 | 499.0 | 512.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.179 | 0.233 | 0.318 | 0.27 |
| 02 | 0.305 | 0.333 | 0.233 | 0.129 |
| 03 | 0.732 | 0.032 | 0.224 | 0.012 |
| 04 | 0.004 | 0.018 | 0.002 | 0.975 |
| 05 | 0.003 | 0.002 | 0.958 | 0.038 |
| 06 | 0.99 | 0.008 | 0.001 | 0.0 |
| 07 | 0.003 | 0.467 | 0.523 | 0.007 |
| 08 | 0.001 | 0.001 | 0.003 | 0.995 |
| 09 | 0.034 | 0.965 | 0.0 | 0.001 |
| 10 | 0.994 | 0.0 | 0.005 | 0.0 |
| 11 | 0.001 | 0.15 | 0.027 | 0.822 |
| 12 | 0.097 | 0.318 | 0.426 | 0.16 |
| 13 | 0.519 | 0.229 | 0.221 | 0.031 |
| 14 | 0.072 | 0.18 | 0.08 | 0.667 |
| 15 | 0.11 | 0.105 | 0.485 | 0.3 |
| 16 | 0.61 | 0.132 | 0.145 | 0.113 |
| 17 | 0.174 | 0.346 | 0.273 | 0.206 |
| 18 | 0.164 | 0.191 | 0.218 | 0.427 |
| 19 | 0.276 | 0.319 | 0.2 | 0.205 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.334 | -0.07 | 0.241 | 0.076 |
| 02 | 0.199 | 0.285 | -0.069 | -0.659 |
| 03 | 1.072 | -2.021 | -0.111 | -2.975 |
| 04 | -3.877 | -2.59 | -4.365 | 1.359 |
| 05 | -4.141 | -4.655 | 1.341 | -1.875 |
| 06 | 1.374 | -3.35 | -4.838 | -5.355 |
| 07 | -4.247 | 0.624 | 0.736 | -3.445 |
| 08 | -4.838 | -5.064 | -4.247 | 1.379 |
| 09 | -1.985 | 1.348 | -5.355 | -5.064 |
| 10 | 1.378 | -5.355 | -3.734 | -5.355 |
| 11 | -5.064 | -0.507 | -2.205 | 1.188 |
| 12 | -0.942 | 0.239 | 0.531 | -0.448 |
| 13 | 0.73 | -0.088 | -0.124 | -2.07 |
| 14 | -1.235 | -0.325 | -1.131 | 0.98 |
| 15 | -0.819 | -0.863 | 0.662 | 0.181 |
| 16 | 0.89 | -0.637 | -0.539 | -0.79 |
| 17 | -0.359 | 0.324 | 0.089 | -0.191 |
| 18 | -0.419 | -0.27 | -0.135 | 0.533 |
| 19 | 0.098 | 0.243 | -0.222 | -0.197 |
| P-value | Threshold |
|---|---|
| 0.001 | 1.31291 |
| 0.0005 | 2.79421 |
| 0.0001 | 5.82916 |