| Motif | NFE2.H12INVITRO.1.SM.B |
| Gene (human) | NFE2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfe2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | NFE2.H12INVITRO.1.SM.B |
| Gene (human) | NFE2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfe2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 18 |
| Consensus | nbvRTGASTCATbvYdvn |
| GC content | 48.93% |
| Information content (bits; total / per base) | 16.637 / 0.924 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 9988 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (34) | 0.821 | 0.9 | 0.727 | 0.819 | 0.765 | 0.867 | 2.591 | 3.058 | 314.55 | 576.886 |
| Mouse | 4 (26) | 0.896 | 0.946 | 0.823 | 0.905 | 0.845 | 0.91 | 2.894 | 3.387 | 252.985 | 475.854 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.762 | 0.782 | 0.747 | 0.761 | 0.744 | 0.753 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.998 | 0.998 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.524 | 0.564 | 0.494 | 0.522 | 0.489 | 0.508 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.339 | 1.432 | 0.111 | 0.162 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.745 | 0.576 | 0.742 | 0.532 |
| batch 2 | 0.768 | 0.523 | 0.739 | 0.455 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | Jun-related {1.1.1} (TFClass) |
| TF subfamily | NFE2 {1.1.1.2} (TFClass) |
| TFClass ID | TFClass: 1.1.1.2.1 |
| HGNC | HGNC:7780 |
| MGI | MGI:97308 |
| EntrezGene (human) | GeneID:4778 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18022 (SSTAR profile) |
| UniProt ID (human) | NFE2_HUMAN |
| UniProt ID (mouse) | NFE2_MOUSE |
| UniProt AC (human) | Q16621 (TFClass) |
| UniProt AC (mouse) | Q07279 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 4 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | NFE2.H12INVITRO.1.SM.B.pcm |
| PWM | NFE2.H12INVITRO.1.SM.B.pwm |
| PFM | NFE2.H12INVITRO.1.SM.B.pfm |
| Alignment | NFE2.H12INVITRO.1.SM.B.words.tsv |
| Threshold to P-value map | NFE2.H12INVITRO.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NFE2.H12INVITRO.1.SM.B_jaspar_format.txt |
| MEME format | NFE2.H12INVITRO.1.SM.B_meme_format.meme |
| Transfac format | NFE2.H12INVITRO.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2137.5 | 1902.5 | 3163.5 | 2784.5 |
| 02 | 1240.5 | 2167.5 | 4726.5 | 1853.5 |
| 03 | 2362.0 | 4053.0 | 2776.0 | 797.0 |
| 04 | 7005.0 | 116.0 | 2789.0 | 78.0 |
| 05 | 57.0 | 95.0 | 47.0 | 9789.0 |
| 06 | 38.0 | 47.0 | 9808.0 | 95.0 |
| 07 | 9857.0 | 111.0 | 14.0 | 6.0 |
| 08 | 13.0 | 4687.0 | 5270.0 | 18.0 |
| 09 | 3.0 | 2.0 | 12.0 | 9971.0 |
| 10 | 82.0 | 9893.0 | 10.0 | 3.0 |
| 11 | 9955.0 | 9.0 | 18.0 | 6.0 |
| 12 | 15.0 | 2147.0 | 126.0 | 7700.0 |
| 13 | 401.0 | 3970.0 | 4241.0 | 1376.0 |
| 14 | 2763.0 | 2727.0 | 4198.0 | 300.0 |
| 15 | 318.0 | 2115.0 | 755.0 | 6800.0 |
| 16 | 1602.0 | 1590.0 | 4168.0 | 2628.0 |
| 17 | 4681.5 | 2020.5 | 2098.5 | 1187.5 |
| 18 | 1892.5 | 3295.5 | 2795.5 | 2004.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.214 | 0.19 | 0.317 | 0.279 |
| 02 | 0.124 | 0.217 | 0.473 | 0.186 |
| 03 | 0.236 | 0.406 | 0.278 | 0.08 |
| 04 | 0.701 | 0.012 | 0.279 | 0.008 |
| 05 | 0.006 | 0.01 | 0.005 | 0.98 |
| 06 | 0.004 | 0.005 | 0.982 | 0.01 |
| 07 | 0.987 | 0.011 | 0.001 | 0.001 |
| 08 | 0.001 | 0.469 | 0.528 | 0.002 |
| 09 | 0.0 | 0.0 | 0.001 | 0.998 |
| 10 | 0.008 | 0.99 | 0.001 | 0.0 |
| 11 | 0.997 | 0.001 | 0.002 | 0.001 |
| 12 | 0.002 | 0.215 | 0.013 | 0.771 |
| 13 | 0.04 | 0.397 | 0.425 | 0.138 |
| 14 | 0.277 | 0.273 | 0.42 | 0.03 |
| 15 | 0.032 | 0.212 | 0.076 | 0.681 |
| 16 | 0.16 | 0.159 | 0.417 | 0.263 |
| 17 | 0.469 | 0.202 | 0.21 | 0.119 |
| 18 | 0.189 | 0.33 | 0.28 | 0.201 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.155 | -0.272 | 0.236 | 0.109 |
| 02 | -0.699 | -0.141 | 0.638 | -0.298 |
| 03 | -0.056 | 0.484 | 0.106 | -1.14 |
| 04 | 1.031 | -3.051 | 0.11 | -3.438 |
| 05 | -3.741 | -3.246 | -3.926 | 1.365 |
| 06 | -4.127 | -3.926 | 1.367 | -3.246 |
| 07 | 1.372 | -3.094 | -5.032 | -5.707 |
| 08 | -5.096 | 0.629 | 0.746 | -4.813 |
| 09 | -6.156 | -6.365 | -5.163 | 1.384 |
| 10 | -3.389 | 1.376 | -5.314 | -6.156 |
| 11 | 1.382 | -5.399 | -4.813 | -5.707 |
| 12 | -4.973 | -0.151 | -2.969 | 1.126 |
| 13 | -1.824 | 0.463 | 0.529 | -0.595 |
| 14 | 0.101 | 0.088 | 0.519 | -2.112 |
| 15 | -2.055 | -0.166 | -1.194 | 1.001 |
| 16 | -0.443 | -0.451 | 0.512 | 0.051 |
| 17 | 0.628 | -0.212 | -0.174 | -0.742 |
| 18 | -0.277 | 0.277 | 0.113 | -0.219 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.33696 |
| 0.0005 | 1.97676 |
| 0.0001 | 5.36806 |