| Motif | NFE2.H12CORE.1.SM.B |
| Gene (human) | NFE2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfe2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | NFE2.H12CORE.1.SM.B |
| Gene (human) | NFE2 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfe2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 19 |
| Consensus | nvATGASTCATbvYdMbbn |
| GC content | 44.55% |
| Information content (bits; total / per base) | 17.986 / 0.947 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8146 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (34) | 0.829 | 0.913 | 0.764 | 0.86 | 0.778 | 0.894 | 2.894 | 3.529 | 323.175 | 629.387 |
| Mouse | 4 (26) | 0.893 | 0.943 | 0.835 | 0.898 | 0.866 | 0.922 | 3.291 | 3.944 | 259.134 | 498.119 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.763 | 0.782 | 0.748 | 0.761 | 0.745 | 0.754 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.998 |
| best | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | 0.998 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.527 | 0.565 | 0.497 | 0.524 | 0.492 | 0.509 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.044 | 1.21 | 0.148 | 0.182 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.751 | 0.581 | 0.729 | 0.526 |
| batch 2 | 0.809 | 0.539 | 0.759 | 0.491 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | Jun-related {1.1.1} (TFClass) |
| TF subfamily | NFE2 {1.1.1.2} (TFClass) |
| TFClass ID | TFClass: 1.1.1.2.1 |
| HGNC | HGNC:7780 |
| MGI | MGI:97308 |
| EntrezGene (human) | GeneID:4778 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18022 (SSTAR profile) |
| UniProt ID (human) | NFE2_HUMAN |
| UniProt ID (mouse) | NFE2_MOUSE |
| UniProt AC (human) | Q16621 (TFClass) |
| UniProt AC (mouse) | Q07279 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 4 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | NFE2.H12CORE.1.SM.B.pcm |
| PWM | NFE2.H12CORE.1.SM.B.pwm |
| PFM | NFE2.H12CORE.1.SM.B.pfm |
| Alignment | NFE2.H12CORE.1.SM.B.words.tsv |
| Threshold to P-value map | NFE2.H12CORE.1.SM.B.thr |
| Motif in other formats | |
| JASPAR format | NFE2.H12CORE.1.SM.B_jaspar_format.txt |
| MEME format | NFE2.H12CORE.1.SM.B_meme_format.meme |
| Transfac format | NFE2.H12CORE.1.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1236.25 | 2220.25 | 2768.25 | 1921.25 |
| 02 | 2293.0 | 2888.0 | 2126.0 | 839.0 |
| 03 | 6640.0 | 140.0 | 1325.0 | 41.0 |
| 04 | 6.0 | 50.0 | 4.0 | 8086.0 |
| 05 | 3.0 | 1.0 | 8034.0 | 108.0 |
| 06 | 8125.0 | 21.0 | 0.0 | 0.0 |
| 07 | 41.0 | 4097.0 | 3974.0 | 34.0 |
| 08 | 0.0 | 0.0 | 17.0 | 8129.0 |
| 09 | 118.0 | 8027.0 | 1.0 | 0.0 |
| 10 | 8134.0 | 1.0 | 10.0 | 1.0 |
| 11 | 3.0 | 1024.0 | 146.0 | 6973.0 |
| 12 | 642.0 | 2941.0 | 3447.0 | 1116.0 |
| 13 | 3811.0 | 2151.0 | 2052.0 | 132.0 |
| 14 | 297.0 | 1212.0 | 331.0 | 6306.0 |
| 15 | 894.0 | 759.0 | 4150.0 | 2343.0 |
| 16 | 5296.0 | 1062.0 | 997.0 | 791.0 |
| 17 | 1038.0 | 3340.0 | 2179.0 | 1589.0 |
| 18 | 1160.5 | 1422.5 | 1886.5 | 3676.5 |
| 19 | 2213.75 | 2607.75 | 1545.75 | 1778.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.152 | 0.273 | 0.34 | 0.236 |
| 02 | 0.281 | 0.355 | 0.261 | 0.103 |
| 03 | 0.815 | 0.017 | 0.163 | 0.005 |
| 04 | 0.001 | 0.006 | 0.0 | 0.993 |
| 05 | 0.0 | 0.0 | 0.986 | 0.013 |
| 06 | 0.997 | 0.003 | 0.0 | 0.0 |
| 07 | 0.005 | 0.503 | 0.488 | 0.004 |
| 08 | 0.0 | 0.0 | 0.002 | 0.998 |
| 09 | 0.014 | 0.985 | 0.0 | 0.0 |
| 10 | 0.999 | 0.0 | 0.001 | 0.0 |
| 11 | 0.0 | 0.126 | 0.018 | 0.856 |
| 12 | 0.079 | 0.361 | 0.423 | 0.137 |
| 13 | 0.468 | 0.264 | 0.252 | 0.016 |
| 14 | 0.036 | 0.149 | 0.041 | 0.774 |
| 15 | 0.11 | 0.093 | 0.509 | 0.288 |
| 16 | 0.65 | 0.13 | 0.122 | 0.097 |
| 17 | 0.127 | 0.41 | 0.267 | 0.195 |
| 18 | 0.142 | 0.175 | 0.232 | 0.451 |
| 19 | 0.272 | 0.32 | 0.19 | 0.218 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.498 | 0.086 | 0.307 | -0.058 |
| 02 | 0.119 | 0.349 | 0.043 | -0.885 |
| 03 | 1.181 | -2.662 | -0.429 | -3.853 |
| 04 | -5.51 | -3.664 | -5.787 | 1.378 |
| 05 | -5.962 | -6.441 | 1.372 | -2.917 |
| 06 | 1.383 | -4.474 | -6.809 | -6.809 |
| 07 | -3.853 | 0.698 | 0.668 | -4.03 |
| 08 | -6.809 | -6.809 | -4.663 | 1.383 |
| 09 | -2.831 | 1.371 | -6.441 | -6.809 |
| 10 | 1.384 | -6.441 | -5.114 | -6.441 |
| 11 | -5.962 | -0.686 | -2.621 | 1.23 |
| 12 | -1.152 | 0.367 | 0.526 | -0.601 |
| 13 | 0.626 | 0.055 | 0.008 | -2.72 |
| 14 | -1.919 | -0.518 | -1.811 | 1.13 |
| 15 | -0.822 | -0.985 | 0.711 | 0.14 |
| 16 | 0.955 | -0.65 | -0.713 | -0.944 |
| 17 | -0.673 | 0.494 | 0.068 | -0.248 |
| 18 | -0.562 | -0.358 | -0.076 | 0.59 |
| 19 | 0.083 | 0.247 | -0.275 | -0.135 |
| P-value | Threshold |
|---|---|
| 0.001 | -1.03919 |
| 0.0005 | 0.77566 |
| 0.0001 | 4.50451 |