NFE2.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFE2.H12CORE.0.P.B
Gene (human)	NFE2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Nfe2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	vnATGACTCAGC
GC content	52.68%
Information content (bits; total / per base)	17.283 / 1.44
Data sources	ChIP-Seq
Aligned words	867

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (34)	0.88	0.97	0.85	0.959	0.881	0.965	5.024	6.298	585.886	976.125
Mouse	4 (26)	0.943	0.982	0.929	0.975	0.944	0.985	5.858	6.519	382.194	695.131

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.766	0.772	0.749	0.755	0.741	0.744
Overall, 4 experiments	best	0.997	0.992	0.997	0.994	0.992	0.988
Methyl HT-SELEX, 1 experiments	median	0.997	0.992	0.994	0.989	0.985	0.979
Methyl HT-SELEX, 1 experiments	best	0.997	0.992	0.994	0.989	0.985	0.979
Non-Methyl HT-SELEX, 3 experiments	median	0.535	0.553	0.504	0.521	0.496	0.509
Non-Methyl HT-SELEX, 3 experiments	best	0.997	0.992	0.997	0.994	0.992	0.988

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.324	3.542	0.201	0.208

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.67	0.407	0.625	0.433
batch 2	0.695	0.264	0.713	0.455

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.1
HGNC	HGNC:7780
MGI	MGI:97308
EntrezGene (human)	GeneID:4778 (SSTAR profile)
EntrezGene (mouse)	GeneID:18022 (SSTAR profile)
UniProt ID (human)	NFE2_HUMAN
UniProt ID (mouse)	NFE2_MOUSE
UniProt AC (human)	Q16621 (TFClass)
UniProt AC (mouse)	Q07279 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	NFE2.H12CORE.0.P.B.pcm
PWM	NFE2.H12CORE.0.P.B.pwm
PFM	NFE2.H12CORE.0.P.B.pfm
Alignment	NFE2.H12CORE.0.P.B.words.tsv
Threshold to P-value map	NFE2.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	NFE2.H12CORE.0.P.B_jaspar_format.txt
MEME format	NFE2.H12CORE.0.P.B_meme_format.meme
Transfac format	NFE2.H12CORE.0.P.B_transfac_format.txt
Homer format	NFE2.H12CORE.0.P.B_homer_format_0.001.txt NFE2.H12CORE.0.P.B_homer_format_0.0005.txt NFE2.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	206.0	239.0	328.0	94.0
02	238.0	254.0	221.0	154.0
03	655.0	5.0	206.0	1.0
04	0.0	1.0	0.0	866.0
05	0.0	0.0	866.0	1.0
06	867.0	0.0	0.0	0.0
07	7.0	732.0	110.0	18.0
08	47.0	2.0	0.0	818.0
09	39.0	819.0	1.0	8.0
10	846.0	0.0	4.0	17.0
11	7.0	0.0	828.0	32.0
12	0.0	861.0	4.0	2.0

PFM

	A	C	G	T
01	0.238	0.276	0.378	0.108
02	0.275	0.293	0.255	0.178
03	0.755	0.006	0.238	0.001
04	0.0	0.001	0.0	0.999
05	0.0	0.0	0.999	0.001
06	1.0	0.0	0.0	0.0
07	0.008	0.844	0.127	0.021
08	0.054	0.002	0.0	0.943
09	0.045	0.945	0.001	0.009
10	0.976	0.0	0.005	0.02
11	0.008	0.0	0.955	0.037
12	0.0	0.993	0.005	0.002

PWM

	A	C	G	T
01	-0.05	0.097	0.412	-0.825
02	0.093	0.157	0.019	-0.339
03	1.101	-3.486	-0.05	-4.397
04	-4.861	-4.397	-4.861	1.379
05	-4.861	-4.861	1.379	-4.397
06	1.38	-4.861	-4.861	-4.861
07	-3.224	1.212	-0.671	-2.406
08	-1.501	-4.081	-4.861	1.322
09	-1.681	1.324	-4.397	-3.115
10	1.356	-4.861	-3.648	-2.458
11	-3.224	-4.861	1.335	-1.869
12	-4.861	1.374	-3.648	-4.081

Standard thresholds

P-value	Threshold
0.001	0.47866
0.0005	2.01787
0.0001	5.274695