MotifNFAT5.H12INVIVO.0.SM.B
Gene (human)NFAT5
(GeneCards)
Gene synonyms (human)KIAA0827, TONEBP
Gene (mouse)Nfat5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnRYGGAAAddYhY
GC content41.5%
Information content (bits; total / per base)12.61 / 0.97
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words6656

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.581 0.969 0.451 0.948 0.592 0.959 1.582 4.839 4.796 52.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.954 0.934 0.884 0.86 0.749 0.75
best 1.0 0.999 0.998 0.998 0.899 0.914
Methyl HT-SELEX, 1 experiments median 0.974 0.962 0.914 0.895 0.77 0.776
best 0.974 0.962 0.914 0.895 0.77 0.776
Non-Methyl HT-SELEX, 3 experiments median 0.935 0.907 0.854 0.824 0.728 0.724
best 1.0 0.999 0.998 0.998 0.899 0.914

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.672 0.409 0.671 0.483
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.5
HGNCHGNC:7774
MGIMGI:1859333
EntrezGene (human)GeneID:10725
(SSTAR profile)
EntrezGene (mouse)GeneID:54446
(SSTAR profile)
UniProt ID (human)NFAT5_HUMAN
UniProt ID (mouse)NFAT5_MOUSE
UniProt AC (human)O94916
(TFClass)
UniProt AC (mouse)Q9WV30
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012400.751600.751126.751527.75
024362.25223.251806.25264.25
03107.03905.040.02604.0
040.00.06656.00.0
050.00.06656.00.0
066656.00.00.00.0
076656.00.00.00.0
085967.036.0295.0358.0
093124.0664.01704.01164.0
101295.0873.01495.02993.0
11968.01198.0515.03975.0
123373.01534.0579.01170.0
13753.04264.0738.0901.0
PFM
ACGT
010.3610.240.1690.23
020.6550.0340.2710.04
030.0160.5870.0060.391
040.00.01.00.0
050.00.01.00.0
061.00.00.00.0
071.00.00.00.0
080.8960.0050.0440.054
090.4690.10.2560.175
100.1950.1310.2250.45
110.1450.180.0770.597
120.5070.230.0870.176
130.1130.6410.1110.135
PWM
ACGT
010.366-0.039-0.389-0.085
020.963-2.00.082-1.833
03-2.7250.852-3.6760.447
04-6.629-6.6291.385-6.629
05-6.629-6.6291.385-6.629
061.385-6.629-6.629-6.629
071.385-6.629-6.629-6.629
081.276-3.775-1.724-1.532
090.629-0.9170.024-0.357
10-0.25-0.644-0.1070.586
11-0.541-0.328-1.170.87
120.706-0.081-1.053-0.352
13-0.7910.94-0.811-0.612
Standard thresholds
P-value Threshold
0.001 3.28621
0.0005 4.84991
0.0001 7.43761