MotifNFAT5.H12INVITRO.1.PS.A
Gene (human)NFAT5
(GeneCards)
Gene synonyms (human)KIAA0827, TONEBP
Gene (mouse)Nfat5
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length14
ConsensusnRTGGAAAWKTMCn
GC content34.25%
Information content (bits; total / per base)17.242 / 1.232
Data sourcesChIP-Seq + HT-SELEX
Aligned words9854

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.579 0.972 0.455 0.965 0.573 0.958 1.589 5.265 6.201 57.0

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.953 0.932 0.865 0.844 0.728 0.732
best 1.0 1.0 0.999 0.999 0.897 0.913
Methyl HT-SELEX, 1 experiments median 0.967 0.95 0.89 0.871 0.748 0.753
best 0.967 0.95 0.89 0.871 0.748 0.753
Non-Methyl HT-SELEX, 3 experiments median 0.94 0.914 0.84 0.817 0.707 0.711
best 1.0 1.0 0.999 0.999 0.897 0.913

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.692 0.438 0.695 0.487
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.5
HGNCHGNC:7774
MGIMGI:1859333
EntrezGene (human)GeneID:10725
(SSTAR profile)
EntrezGene (mouse)GeneID:54446
(SSTAR profile)
UniProt ID (human)NFAT5_HUMAN
UniProt ID (mouse)NFAT5_MOUSE
UniProt AC (human)O94916
(TFClass)
UniProt AC (mouse)Q9WV30
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
013708.252254.251773.252118.25
024097.25509.255200.2547.25
0320.0572.02.09260.0
040.02.09851.01.0
050.01.09850.03.0
069833.01.017.03.0
079843.02.06.03.0
089519.05.011.0319.0
096306.076.0960.02512.0
10795.0224.0989.07846.0
11130.0117.017.09590.0
124541.02903.019.02391.0
13298.758000.75268.751285.75
143484.51782.51835.52751.5
PFM
ACGT
010.3760.2290.180.215
020.4160.0520.5280.005
030.0020.0580.00.94
040.00.01.00.0
050.00.01.00.0
060.9980.00.0020.0
070.9990.00.0010.0
080.9660.0010.0010.032
090.640.0080.0970.255
100.0810.0230.10.796
110.0130.0120.0020.973
120.4610.2950.0020.243
130.030.8120.0270.13
140.3540.1810.1860.279
PWM
ACGT
010.409-0.089-0.328-0.151
020.508-1.5730.747-3.907
03-4.706-1.457-6.3521.323
04-6.978-6.3521.385-6.617
05-6.978-6.6171.385-6.143
061.383-6.617-4.85-6.143
071.384-6.352-5.694-6.143
081.351-5.823-5.223-2.038
090.939-3.45-0.9410.019
10-1.129-2.388-0.9111.158
11-2.925-3.029-4.851.358
120.6110.164-4.752-0.03
13-2.1031.177-2.208-0.649
140.346-0.323-0.2940.11
Standard thresholds
P-value Threshold
0.001 -0.75034
0.0005 1.07501
0.0001 4.809015