MotifNFAC4.H12INVITRO.1.SM.B
Gene (human)NFATC4
(GeneCards)
Gene synonyms (human)NFAT3
Gene (mouse)Nfatc4
Gene synonyms (mouse)Nfat3
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnhACGGAAAvdn
GC content40.46%
Information content (bits; total / per base)12.444 / 1.037
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9555

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (4) 0.527 0.53 0.343 0.35 0.539 0.546 1.11 1.136 0.0 0

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.984 0.972 0.978 0.964 0.963 0.946
best 0.995 0.991 0.991 0.985 0.985 0.977
Methyl HT-SELEX, 2 experiments median 0.985 0.974 0.978 0.965 0.963 0.946
best 0.995 0.991 0.991 0.985 0.982 0.973
Non-Methyl HT-SELEX, 2 experiments median 0.965 0.942 0.95 0.924 0.907 0.886
best 0.993 0.988 0.991 0.984 0.985 0.977
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.4
HGNCHGNC:7778
MGIMGI:1920431
EntrezGene (human)GeneID:4776
(SSTAR profile)
EntrezGene (mouse)GeneID:73181
(SSTAR profile)
UniProt ID (human)NFAC4_HUMAN
UniProt ID (mouse)NFAC4_MOUSE
UniProt AC (human)Q14934
(TFClass)
UniProt AC (mouse)Q8K120
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
011966.752532.752582.752472.75
023973.752207.751211.752161.75
037206.099.01997.0253.0
041.05993.00.03561.0
050.00.09555.00.0
060.00.09555.00.0
079555.00.00.00.0
089555.00.00.00.0
099253.0218.02.082.0
103565.03194.01579.01217.0
113505.25851.25952.254246.25
122415.51613.52248.53277.5
PFM
ACGT
010.2060.2650.270.259
020.4160.2310.1270.226
030.7540.010.2090.026
040.00.6270.00.373
050.00.01.00.0
060.00.01.00.0
071.00.00.00.0
081.00.00.00.0
090.9680.0230.00.009
100.3730.3340.1650.127
110.3670.0890.10.444
120.2530.1690.2350.343
PWM
ACGT
01-0.1940.0580.0780.035
020.509-0.079-0.678-0.1
031.104-3.161-0.179-2.237
04-6.5880.919-6.950.399
05-6.95-6.951.386-6.95
06-6.95-6.951.386-6.95
071.386-6.95-6.95-6.95
081.386-6.95-6.95-6.95
091.353-2.385-6.323-3.345
100.40.29-0.413-0.673
110.383-1.03-0.9180.575
120.011-0.392-0.060.316
Standard thresholds
P-value Threshold
0.001 1.90392
0.0005 4.238375
0.0001 7.844875