MotifNFAC3.H12INVIVO.1.P.C
Gene (human)NFATC3
(GeneCards)
Gene synonyms (human)NFAT4
Gene (mouse)Nfatc3
Gene synonyms (mouse)Nfat4
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length10
ConsensusvvWGGAAARd
GC content39.76%
Information content (bits; total / per base)9.119 / 0.912
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.589 0.602 0.423 0.433 0.646 0.66 1.621 1.68 7.94 10.347

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.974 0.954 0.957 0.933 0.915 0.888
best 0.975 0.959 0.961 0.936 0.924 0.897
Methyl HT-SELEX, 1 experiments median 0.975 0.959 0.953 0.931 0.906 0.879
best 0.975 0.959 0.953 0.931 0.906 0.879
Non-Methyl HT-SELEX, 1 experiments median 0.972 0.949 0.961 0.936 0.924 0.897
best 0.972 0.949 0.961 0.936 0.924 0.897
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.3
HGNCHGNC:7777
MGIMGI:103296
EntrezGene (human)GeneID:4775
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NFAC3_HUMAN
UniProt ID (mouse)NFAC3_MOUSE
UniProt AC (human)Q12968
(TFClass)
UniProt AC (mouse)P97305
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01497.0129.0288.086.0
02446.0216.0301.037.0
03501.022.099.0378.0
04109.02.0877.012.0
0534.019.0937.010.0
06974.05.015.06.0
07730.016.0246.08.0
08887.019.089.05.0
09538.088.0346.028.0
10544.0105.0157.0194.0
PFM
ACGT
010.4970.1290.2880.086
020.4460.2160.3010.037
030.5010.0220.0990.378
040.1090.0020.8770.012
050.0340.0190.9370.01
060.9740.0050.0150.006
070.730.0160.2460.008
080.8870.0190.0890.005
090.5380.0880.3460.028
100.5440.1050.1570.194
PWM
ACGT
010.684-0.6550.141-1.054
020.576-0.1450.184-1.872
030.692-2.362-0.9160.411
04-0.821-4.2131.25-2.909
05-1.952-2.4971.316-3.066
061.355-3.622-2.711-3.484
071.067-2.653-0.016-3.253
081.261-2.497-1.02-3.622
090.763-1.0320.323-2.136
100.774-0.858-0.461-0.252
Standard thresholds
P-value Threshold
0.001 4.939565
0.0005 5.786385
0.0001 7.391385