NFAC3.H12INVIVO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFAC3.H12INVIVO.0.SM.B
Gene (human)	NFATC3 (GeneCards)
Gene synonyms (human)	NFAT4
Gene (mouse)	Nfatc3
Gene synonyms (mouse)	Nfat4
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nvnATGGAAAvdn
GC content	38.84%
Information content (bits; total / per base)	13.281 / 1.022
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	2084

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.603	0.632	0.462	0.494	0.571	0.583	1.525	1.629	14.308	22.721

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.994	0.99	0.991	0.985	0.98	0.971
Overall, 2 experiments	best	0.995	0.991	0.992	0.986	0.982	0.973
Methyl HT-SELEX, 1 experiments	median	0.995	0.991	0.992	0.986	0.982	0.973
Methyl HT-SELEX, 1 experiments	best	0.995	0.991	0.992	0.986	0.982	0.973
Non-Methyl HT-SELEX, 1 experiments	median	0.993	0.988	0.99	0.983	0.979	0.969
Non-Methyl HT-SELEX, 1 experiments	best	0.993	0.988	0.99	0.983	0.979	0.969

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Rel homology region (RHR) factors {6.1} (TFClass)
TF family	NFAT-related {6.1.3} (TFClass)
TF subfamily	{6.1.3.0} (TFClass)
TFClass ID	TFClass: 6.1.3.0.3
HGNC	HGNC:7777
MGI	MGI:103296
EntrezGene (human)	GeneID:4775 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	NFAC3_HUMAN
UniProt ID (mouse)	NFAC3_MOUSE
UniProt AC (human)	Q12968 (TFClass)
UniProt AC (mouse)	P97305 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	NFAC3.H12INVIVO.0.SM.B.pcm
PWM	NFAC3.H12INVIVO.0.SM.B.pwm
PFM	NFAC3.H12INVIVO.0.SM.B.pfm
Alignment	NFAC3.H12INVIVO.0.SM.B.words.tsv
Threshold to P-value map	NFAC3.H12INVIVO.0.SM.B.thr
Motif in other formats
JASPAR format	NFAC3.H12INVIVO.0.SM.B_jaspar_format.txt
MEME format	NFAC3.H12INVIVO.0.SM.B_meme_format.meme
Transfac format	NFAC3.H12INVIVO.0.SM.B_transfac_format.txt
Homer format	NFAC3.H12INVIVO.0.SM.B_homer_format_0.001.txt NFAC3.H12INVIVO.0.SM.B_homer_format_0.0005.txt NFAC3.H12INVIVO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	482.5	532.5	547.5	521.5
02	387.25	706.25	684.25	306.25
03	616.0	690.0	290.0	488.0
04	1524.0	25.0	532.0	3.0
05	0.0	21.0	0.0	2063.0
06	0.0	0.0	2084.0	0.0
07	0.0	0.0	2084.0	0.0
08	2084.0	0.0	0.0	0.0
09	2084.0	0.0	0.0	0.0
10	1999.0	64.0	1.0	20.0
11	850.0	567.0	376.0	291.0
12	615.5	227.5	238.5	1002.5
13	597.0	376.0	475.0	636.0

PFM

	A	C	G	T
01	0.232	0.256	0.263	0.25
02	0.186	0.339	0.328	0.147
03	0.296	0.331	0.139	0.234
04	0.731	0.012	0.255	0.001
05	0.0	0.01	0.0	0.99
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	1.0	0.0	0.0	0.0
09	1.0	0.0	0.0	0.0
10	0.959	0.031	0.0	0.01
11	0.408	0.272	0.18	0.14
12	0.295	0.109	0.114	0.481
13	0.286	0.18	0.228	0.305

PWM

	A	C	G	T
01	-0.076	0.022	0.049	0.001
02	-0.295	0.303	0.272	-0.529
03	0.167	0.28	-0.583	-0.065
04	1.071	-2.967	0.021	-4.668
05	-5.612	-3.128	-5.612	1.373
06	-5.612	-5.612	1.384	-5.612
07	-5.612	-5.612	1.384	-5.612
08	1.384	-5.612	-5.612	-5.612
09	1.384	-5.612	-5.612	-5.612
10	1.342	-2.071	-5.191	-3.172
11	0.488	0.084	-0.325	-0.58
12	0.166	-0.824	-0.777	0.653
13	0.136	-0.325	-0.092	0.199

Standard thresholds

P-value	Threshold
0.001	2.297615
0.0005	3.544215
0.0001	7.413275