NFAC3.H12INVITRO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFAC3.H12INVITRO.1.P.C
Gene (human)	NFATC3 (GeneCards)
Gene synonyms (human)	NFAT4
Gene (mouse)	Nfatc3
Gene synonyms (mouse)	Nfat4
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	10
Consensus	vvvWGGARAR
GC content	45.78%
Information content (bits; total / per base)	9.158 / 0.916
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.576	0.59	0.408	0.411	0.653	0.665	1.599	1.654	6.304	9.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.976	0.961	0.948	0.926	0.906	0.878
Overall, 2 experiments	best	0.979	0.966	0.957	0.936	0.925	0.898
Methyl HT-SELEX, 1 experiments	median	0.973	0.956	0.94	0.915	0.887	0.857
Methyl HT-SELEX, 1 experiments	best	0.973	0.956	0.94	0.915	0.887	0.857
Non-Methyl HT-SELEX, 1 experiments	median	0.979	0.966	0.957	0.936	0.925	0.898
Non-Methyl HT-SELEX, 1 experiments	best	0.979	0.966	0.957	0.936	0.925	0.898

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Rel homology region (RHR) factors {6.1} (TFClass)
TF family	NFAT-related {6.1.3} (TFClass)
TF subfamily	{6.1.3.0} (TFClass)
TFClass ID	TFClass: 6.1.3.0.3
HGNC	HGNC:7777
MGI	MGI:103296
EntrezGene (human)	GeneID:4775 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	NFAC3_HUMAN
UniProt ID (mouse)	NFAC3_MOUSE
UniProt AC (human)	Q12968 (TFClass)
UniProt AC (mouse)	P97305 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	NFAC3.H12INVITRO.1.P.C.pcm
PWM	NFAC3.H12INVITRO.1.P.C.pwm
PFM	NFAC3.H12INVITRO.1.P.C.pfm
Alignment	NFAC3.H12INVITRO.1.P.C.words.tsv
Threshold to P-value map	NFAC3.H12INVITRO.1.P.C.thr
Motif in other formats
JASPAR format	NFAC3.H12INVITRO.1.P.C_jaspar_format.txt
MEME format	NFAC3.H12INVITRO.1.P.C_meme_format.meme
Transfac format	NFAC3.H12INVITRO.1.P.C_transfac_format.txt
Homer format	NFAC3.H12INVITRO.1.P.C_homer_format_0.001.txt NFAC3.H12INVITRO.1.P.C_homer_format_0.0005.txt NFAC3.H12INVITRO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	313.0	151.0	403.0	133.0
02	392.0	100.0	429.0	79.0
03	423.0	309.0	245.0	23.0
04	447.0	11.0	128.0	414.0
05	37.0	3.0	951.0	9.0
06	11.0	11.0	968.0	10.0
07	987.0	9.0	2.0	2.0
08	684.0	14.0	293.0	9.0
09	833.0	28.0	111.0	28.0
10	519.0	65.0	347.0	69.0

PFM

	A	C	G	T
01	0.313	0.151	0.403	0.133
02	0.392	0.1	0.429	0.079
03	0.423	0.309	0.245	0.023
04	0.447	0.011	0.128	0.414
05	0.037	0.003	0.951	0.009
06	0.011	0.011	0.968	0.01
07	0.987	0.009	0.002	0.002
08	0.684	0.014	0.293	0.009
09	0.833	0.028	0.111	0.028
10	0.519	0.065	0.347	0.069

PWM

	A	C	G	T
01	0.223	-0.5	0.475	-0.625
02	0.447	-0.906	0.537	-1.137
03	0.523	0.211	-0.02	-2.32
04	0.578	-2.985	-0.663	0.502
05	-1.872	-3.975	1.331	-3.156
06	-2.985	-2.985	1.349	-3.066
07	1.368	-3.156	-4.213	-4.213
08	1.002	-2.773	0.158	-3.156
09	1.199	-2.136	-0.803	-2.136
10	0.727	-1.328	0.326	-1.27

Standard thresholds

P-value	Threshold
0.001	4.97448
0.0005	5.8537
0.0001	7.505045