NFAC3.H12CORE.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NFAC3.H12CORE.1.P.C
Gene (human)	NFATC3 (GeneCards)
Gene synonyms (human)	NFAT4
Gene (mouse)	Nfatc3
Gene synonyms (mouse)	Nfat4
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	10
Consensus	vvWGGAAARd
GC content	39.76%
Information content (bits; total / per base)	9.119 / 0.912
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.589	0.602	0.423	0.433	0.646	0.66	1.621	1.68	7.94	10.347

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.974	0.954	0.957	0.933	0.915	0.888
Overall, 2 experiments	best	0.975	0.959	0.961	0.936	0.924	0.897
Methyl HT-SELEX, 1 experiments	median	0.975	0.959	0.953	0.931	0.906	0.879
Methyl HT-SELEX, 1 experiments	best	0.975	0.959	0.953	0.931	0.906	0.879
Non-Methyl HT-SELEX, 1 experiments	median	0.972	0.949	0.961	0.936	0.924	0.897
Non-Methyl HT-SELEX, 1 experiments	best	0.972	0.949	0.961	0.936	0.924	0.897

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Rel homology region (RHR) factors {6.1} (TFClass)
TF family	NFAT-related {6.1.3} (TFClass)
TF subfamily	{6.1.3.0} (TFClass)
TFClass ID	TFClass: 6.1.3.0.3
HGNC	HGNC:7777
MGI	MGI:103296
EntrezGene (human)	GeneID:4775 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	NFAC3_HUMAN
UniProt ID (mouse)	NFAC3_MOUSE
UniProt AC (human)	Q12968 (TFClass)
UniProt AC (mouse)	P97305 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	NFAC3.H12CORE.1.P.C.pcm
PWM	NFAC3.H12CORE.1.P.C.pwm
PFM	NFAC3.H12CORE.1.P.C.pfm
Alignment	NFAC3.H12CORE.1.P.C.words.tsv
Threshold to P-value map	NFAC3.H12CORE.1.P.C.thr
Motif in other formats
JASPAR format	NFAC3.H12CORE.1.P.C_jaspar_format.txt
MEME format	NFAC3.H12CORE.1.P.C_meme_format.meme
Transfac format	NFAC3.H12CORE.1.P.C_transfac_format.txt
Homer format	NFAC3.H12CORE.1.P.C_homer_format_0.001.txt NFAC3.H12CORE.1.P.C_homer_format_0.0005.txt NFAC3.H12CORE.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	497.0	129.0	288.0	86.0
02	446.0	216.0	301.0	37.0
03	501.0	22.0	99.0	378.0
04	109.0	2.0	877.0	12.0
05	34.0	19.0	937.0	10.0
06	974.0	5.0	15.0	6.0
07	730.0	16.0	246.0	8.0
08	887.0	19.0	89.0	5.0
09	538.0	88.0	346.0	28.0
10	544.0	105.0	157.0	194.0

PFM

	A	C	G	T
01	0.497	0.129	0.288	0.086
02	0.446	0.216	0.301	0.037
03	0.501	0.022	0.099	0.378
04	0.109	0.002	0.877	0.012
05	0.034	0.019	0.937	0.01
06	0.974	0.005	0.015	0.006
07	0.73	0.016	0.246	0.008
08	0.887	0.019	0.089	0.005
09	0.538	0.088	0.346	0.028
10	0.544	0.105	0.157	0.194

PWM

	A	C	G	T
01	0.684	-0.655	0.141	-1.054
02	0.576	-0.145	0.184	-1.872
03	0.692	-2.362	-0.916	0.411
04	-0.821	-4.213	1.25	-2.909
05	-1.952	-2.497	1.316	-3.066
06	1.355	-3.622	-2.711	-3.484
07	1.067	-2.653	-0.016	-3.253
08	1.261	-2.497	-1.02	-3.622
09	0.763	-1.032	0.323	-2.136
10	0.774	-0.858	-0.461	-0.252

Standard thresholds

P-value	Threshold
0.001	4.939565
0.0005	5.786385
0.0001	7.391385