MotifNFAC3.H12CORE.0.SM.B
Gene (human)NFATC3
(GeneCards)
Gene synonyms (human)NFAT4
Gene (mouse)Nfatc3
Gene synonyms (mouse)Nfat4
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length14
ConsensusnbnRCGGAAAvWnn
GC content42.27%
Information content (bits; total / per base)13.0 / 0.929
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9710

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.607 0.64 0.476 0.514 0.572 0.586 1.501 1.598 15.131 20.432

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.994 0.99 0.992 0.986 0.985 0.977
best 0.997 0.994 0.995 0.992 0.991 0.986
Methyl HT-SELEX, 1 experiments median 0.997 0.994 0.995 0.992 0.991 0.986
best 0.997 0.994 0.995 0.992 0.991 0.986
Non-Methyl HT-SELEX, 1 experiments median 0.992 0.985 0.988 0.98 0.98 0.969
best 0.992 0.985 0.988 0.98 0.98 0.969
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.3
HGNCHGNC:7777
MGIMGI:103296
EntrezGene (human)GeneID:4775
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NFAC3_HUMAN
UniProt ID (mouse)NFAC3_MOUSE
UniProt AC (human)Q12968
(TFClass)
UniProt AC (mouse)P97305
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
011812.52332.53085.52479.5
021246.753077.753302.752082.75
033523.02006.01625.02556.0
046593.030.02919.0168.0
050.05723.00.03987.0
060.00.09710.00.0
070.00.09710.00.0
089710.00.00.00.0
099710.00.00.00.0
109689.018.00.03.0
114058.03238.01583.0831.0
123587.0524.0442.05157.0
133025.51277.52253.53153.5
142229.752415.752194.752869.75
PFM
ACGT
010.1870.240.3180.255
020.1280.3170.340.214
030.3630.2070.1670.263
040.6790.0030.3010.017
050.00.5890.00.411
060.00.01.00.0
070.00.01.00.0
081.00.00.00.0
091.00.00.00.0
100.9980.0020.00.0
110.4180.3330.1630.086
120.3690.0540.0460.531
130.3120.1320.2320.325
140.230.2490.2260.296
PWM
ACGT
01-0.292-0.040.240.021
02-0.6650.2370.308-0.153
030.372-0.191-0.4010.052
040.999-4.3210.184-2.658
05-6.9650.857-6.9650.496
06-6.965-6.9651.386-6.965
07-6.965-6.9651.386-6.965
081.386-6.965-6.965-6.965
091.386-6.965-6.965-6.965
101.383-4.785-6.965-6.129
110.5130.288-0.427-1.07
120.39-1.53-1.6990.753
130.22-0.641-0.0740.261
14-0.085-0.005-0.1010.167
Standard thresholds
P-value Threshold
0.001 0.99611
0.0005 2.30351
0.0001 7.69401