MotifNFAC2.H12INVIVO.4.M.B
Gene (human)NFATC2
(GeneCards)
Gene synonyms (human)NFAT1, NFATP
Gene (mouse)Nfatc2
Gene synonyms (mouse)Nfat1, Nfatp
LOGO
LOGO (reverse complement)
Motif subtype4
Quality
B
Motif length19
ConsensusdKWYYvnbhACGGAAAhWn
GC content39.77%
Information content (bits; total / per base)16.525 / 0.87
Data sourcesMethyl-HT-SELEX
Aligned words2149

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (10) 0.739 0.764 0.594 0.628 0.703 0.722 1.928 2.08 42.533 89.886
Mouse 1 (7) 0.795 0.808 0.647 0.657 0.731 0.736 1.979 2.021 75.409 85.824

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.992 0.988 0.98 0.971 0.94 0.927
best 1.0 1.0 0.999 0.999 0.986 0.985
Methyl HT-SELEX, 2 experiments median 0.986 0.98 0.972 0.96 0.935 0.922
best 1.0 1.0 0.999 0.999 0.986 0.985
Non-Methyl HT-SELEX, 2 experiments median 0.992 0.988 0.98 0.971 0.94 0.927
best 0.999 0.998 0.988 0.985 0.949 0.941
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.2
HGNCHGNC:7776
MGIMGI:102463
EntrezGene (human)GeneID:4773
(SSTAR profile)
EntrezGene (mouse)GeneID:18019
(SSTAR profile)
UniProt ID (human)NFAC2_HUMAN
UniProt ID (mouse)NFAC2_MOUSE
UniProt AC (human)Q13469
(TFClass)
UniProt AC (mouse)Q60591
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01377.25351.25394.251026.25
02235.5202.5303.51407.5
03205.0119.0140.01685.0
04175.0764.0112.01098.0
05163.01578.097.0311.0
06340.01012.0509.0288.0
07440.0409.0724.0576.0
08281.0574.0321.0973.0
091071.0306.0104.0668.0
101669.04.0429.047.0
110.01677.00.0472.0
120.00.02149.00.0
130.00.02149.00.0
142149.00.00.00.0
152149.00.00.00.0
162060.067.02.020.0
171054.0495.0266.0334.0
18706.5123.5119.51199.5
19667.25388.25349.25744.25
PFM
ACGT
010.1760.1630.1830.478
020.110.0940.1410.655
030.0950.0550.0650.784
040.0810.3560.0520.511
050.0760.7340.0450.145
060.1580.4710.2370.134
070.2050.190.3370.268
080.1310.2670.1490.453
090.4980.1420.0480.311
100.7770.0020.20.022
110.00.780.00.22
120.00.01.00.0
130.00.01.00.0
141.00.00.00.0
151.00.00.00.0
160.9590.0310.0010.009
170.490.230.1240.155
180.3290.0570.0560.558
190.310.1810.1630.346
PWM
ACGT
01-0.352-0.423-0.3080.646
02-0.82-0.97-0.5680.961
03-0.958-1.495-1.3351.141
04-1.1140.351-1.5550.713
05-1.1851.075-1.696-0.544
06-0.4550.632-0.054-0.62
07-0.199-0.2720.2970.069
08-0.6450.066-0.5130.592
090.688-0.56-1.6270.217
101.131-4.512-0.224-2.4
11-5.6391.136-5.639-0.129
12-5.639-5.6391.384-5.639
13-5.639-5.6391.384-5.639
141.384-5.639-5.639-5.639
151.384-5.639-5.639-5.639
161.341-2.057-4.924-3.203
170.672-0.082-0.699-0.473
180.273-1.458-1.4910.801
190.216-0.323-0.4290.325
Standard thresholds
P-value Threshold
0.001 0.97626
0.0005 2.56161
0.0001 5.90161