MotifNFAC2.H12INVITRO.0.P.B
Gene (human)NFATC2
(GeneCards)
Gene synonyms (human)NFAT1, NFATP
Gene (mouse)Nfatc2
Gene synonyms (mouse)Nfat1, Nfatp
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length20
ConsensusvvvvWGGAARvdnWdWvWvd
GC content41.52%
Information content (bits; total / per base)12.814 / 0.641
Data sourcesChIP-Seq
Aligned words1000

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (10) 0.84 0.879 0.751 0.812 0.889 0.9 3.649 3.843 157.327 243.959
Mouse 1 (7) 0.859 0.87 0.741 0.76 0.855 0.859 2.886 2.908 160.886 178.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.945 0.912 0.921 0.883 0.876 0.837
best 0.98 0.967 0.97 0.952 0.944 0.921
Methyl HT-SELEX, 2 experiments median 0.927 0.886 0.9 0.856 0.852 0.811
best 0.966 0.942 0.948 0.919 0.907 0.875
Non-Methyl HT-SELEX, 2 experiments median 0.952 0.924 0.932 0.899 0.894 0.859
best 0.98 0.967 0.97 0.952 0.944 0.921
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.2
HGNCHGNC:7776
MGIMGI:102463
EntrezGene (human)GeneID:4773
(SSTAR profile)
EntrezGene (mouse)GeneID:18019
(SSTAR profile)
UniProt ID (human)NFAC2_HUMAN
UniProt ID (mouse)NFAC2_MOUSE
UniProt AC (human)Q13469
(TFClass)
UniProt AC (mouse)Q60591
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01180.0268.0416.0136.0
02174.0266.0424.0136.0
03525.0137.0251.087.0
04483.0135.0283.099.0
05240.053.071.0636.0
068.00.0992.00.0
072.04.0994.00.0
08949.020.026.05.0
09927.07.058.08.0
10797.045.096.062.0
11499.0157.0198.0146.0
12478.046.0115.0361.0
13379.0187.0218.0216.0
14166.0119.061.0654.0
15149.083.0567.0201.0
16648.077.0110.0165.0
17201.0300.0411.088.0
18165.098.0112.0625.0
19226.0488.0150.0136.0
20589.0106.0155.0150.0
PFM
ACGT
010.180.2680.4160.136
020.1740.2660.4240.136
030.5250.1370.2510.087
040.4830.1350.2830.099
050.240.0530.0710.636
060.0080.00.9920.0
070.0020.0040.9940.0
080.9490.020.0260.005
090.9270.0070.0580.008
100.7970.0450.0960.062
110.4990.1570.1980.146
120.4780.0460.1150.361
130.3790.1870.2180.216
140.1660.1190.0610.654
150.1490.0830.5670.201
160.6480.0770.110.165
170.2010.30.4110.088
180.1650.0980.1120.625
190.2260.4880.150.136
200.5890.1060.1550.15
PWM
ACGT
01-0.3260.0690.506-0.603
02-0.3590.0620.525-0.603
030.738-0.5960.004-1.043
040.655-0.610.123-0.916
05-0.041-1.526-1.2420.93
06-3.253-4.9821.373-4.982
07-4.213-3.7831.375-4.982
081.329-2.45-2.206-3.622
091.305-3.362-1.439-3.253
101.155-1.684-0.946-1.374
110.688-0.461-0.231-0.533
120.645-1.663-0.7690.365
130.414-0.288-0.136-0.145
14-0.406-0.735-1.390.957
15-0.513-1.0890.815-0.216
160.948-1.162-0.812-0.412
17-0.2160.1810.494-1.032
18-0.412-0.926-0.7950.912
19-0.10.666-0.506-0.603
200.853-0.849-0.474-0.506
Standard thresholds
P-value Threshold
0.001 3.99546
0.0005 5.01306
0.0001 7.07596