MotifNFAC2.H12CORE.1.PS.A
Gene (human)NFATC2
(GeneCards)
Gene synonyms (human)NFAT1, NFATP
Gene (mouse)Nfatc2
Gene synonyms (mouse)Nfat1, Nfatp
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length11
ConsensusnvRWGGAAWvd
GC content38.46%
Information content (bits; total / per base)10.379 / 0.944
Data sourcesChIP-Seq + HT-SELEX
Aligned words1010

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (10) 0.745 0.785 0.541 0.629 0.788 0.811 2.546 2.723 87.112 164.056
Mouse 1 (7) 0.829 0.834 0.672 0.683 0.814 0.823 2.403 2.454 128.149 137.921

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.978 0.962 0.963 0.943 0.935 0.91
best 0.993 0.988 0.991 0.985 0.985 0.976
Methyl HT-SELEX, 2 experiments median 0.961 0.936 0.943 0.914 0.909 0.877
best 0.988 0.979 0.977 0.965 0.951 0.934
Non-Methyl HT-SELEX, 2 experiments median 0.98 0.966 0.97 0.953 0.952 0.931
best 0.993 0.988 0.991 0.985 0.985 0.976
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.2
HGNCHGNC:7776
MGIMGI:102463
EntrezGene (human)GeneID:4773
(SSTAR profile)
EntrezGene (mouse)GeneID:18019
(SSTAR profile)
UniProt ID (human)NFAC2_HUMAN
UniProt ID (mouse)NFAC2_MOUSE
UniProt AC (human)Q13469
(TFClass)
UniProt AC (mouse)Q60591
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 1 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01219.0239.0393.0159.0
02570.0158.0197.085.0
03552.087.0310.061.0
04166.038.057.0749.0
057.00.01001.02.0
067.013.0986.04.0
07990.08.08.04.0
08970.09.029.02.0
09787.057.042.0124.0
10414.0238.0213.0145.0
11472.047.0143.0348.0
PFM
ACGT
010.2170.2370.3890.157
020.5640.1560.1950.084
030.5470.0860.3070.06
040.1640.0380.0560.742
050.0070.00.9910.002
060.0070.0130.9760.004
070.980.0080.0080.004
080.960.0090.0290.002
090.7790.0560.0420.123
100.410.2360.2110.144
110.4670.0470.1420.345
PWM
ACGT
01-0.141-0.0550.44-0.459
020.81-0.465-0.246-1.075
030.778-1.0530.204-1.399
04-0.416-1.856-1.4651.083
05-3.372-4.991.372-4.222
06-3.372-2.8481.357-3.793
071.361-3.263-3.263-3.793
081.341-3.165-2.113-4.222
091.132-1.465-1.76-0.704
100.492-0.059-0.169-0.55
110.622-1.652-0.5630.319
Standard thresholds
P-value Threshold
0.001 4.68438
0.0005 5.63614
0.0001 7.450495