MotifNFAC1.H12INVIVO.2.SM.B
Gene (human)NFATC1
(GeneCards)
Gene synonyms (human)NFAT2, NFATC
Gene (mouse)Nfatc1
Gene synonyms (mouse)Nfat2, Nfatc
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length20
ConsensusnddWhYnnbnATGGAAAvWn
GC content37.19%
Information content (bits; total / per base)15.632 / 0.782
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9289

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (16) 0.597 0.726 0.451 0.588 0.578 0.726 1.46 2.181 15.661 45.347
Mouse 3 (18) 0.711 0.81 0.576 0.671 0.691 0.791 2.013 2.46 113.935 204.585

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.954 0.935 0.877 0.858 0.734 0.745
best 0.999 0.999 0.996 0.995 0.959 0.957
Methyl HT-SELEX, 2 experiments median 0.988 0.984 0.965 0.956 0.876 0.878
best 0.999 0.999 0.996 0.995 0.959 0.957
Non-Methyl HT-SELEX, 4 experiments median 0.884 0.866 0.737 0.739 0.621 0.645
best 0.995 0.994 0.949 0.942 0.789 0.807
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.1
HGNCHGNC:7775
MGIMGI:102469
EntrezGene (human)GeneID:4772
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NFAC1_HUMAN
UniProt ID (mouse)NFAC1_MOUSE
UniProt AC (human)O95644
(TFClass)
UniProt AC (mouse)O88942
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 3 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012437.751615.752062.753172.75
021433.01397.01869.04590.0
031369.01108.01167.05645.0
041208.0770.0970.06341.0
05915.03190.0809.04375.0
06737.05203.0775.02574.0
072334.03260.01316.02379.0
082212.02311.01650.03116.0
091301.04017.01484.02487.0
102971.02550.01317.02451.0
117325.0106.01759.099.0
126.0781.00.08502.0
130.00.09289.00.0
140.00.09289.00.0
159289.00.00.00.0
169289.00.00.00.0
178966.0304.04.015.0
184617.02602.01373.0697.0
192975.25745.25483.255085.25
202596.251585.251933.253174.25
PFM
ACGT
010.2620.1740.2220.342
020.1540.150.2010.494
030.1470.1190.1260.608
040.130.0830.1040.683
050.0990.3430.0870.471
060.0790.560.0830.277
070.2510.3510.1420.256
080.2380.2490.1780.335
090.140.4320.160.268
100.320.2750.1420.264
110.7890.0110.1890.011
120.0010.0840.00.915
130.00.01.00.0
140.00.01.00.0
151.00.00.00.0
161.00.00.00.0
170.9650.0330.00.002
180.4970.280.1480.075
190.320.080.0520.547
200.2790.1710.2080.342
PWM
ACGT
010.048-0.362-0.1180.312
02-0.482-0.508-0.2170.681
03-0.528-0.739-0.6870.888
04-0.653-1.102-0.8721.004
05-0.930.317-1.0530.633
06-1.1460.806-1.0950.103
070.0050.339-0.5670.024
08-0.049-0.005-0.3410.294
09-0.5790.548-0.4470.068
100.2460.093-0.5660.054
111.148-3.067-0.277-3.133
12-5.637-1.088-6.9251.297
13-6.925-6.9251.386-6.925
14-6.925-6.9251.386-6.925
151.386-6.925-6.925-6.925
161.386-6.925-6.925-6.925
171.35-2.027-5.913-4.901
180.6870.114-0.525-1.201
190.248-1.134-1.5660.783
200.111-0.381-0.1830.312
Standard thresholds
P-value Threshold
0.001 0.54076
0.0005 2.36501
0.0001 6.21051