MotifNFAC1.H12INVITRO.3.SM.B
Gene (human)NFATC1
(GeneCards)
Gene synonyms (human)NFAT2, NFATC
Gene (mouse)Nfatc1
Gene synonyms (mouse)Nfat2, Nfatc
LOGO
LOGO (reverse complement)
Motif subtype3
Quality
B
Motif length14
ConsensusnRCGGAAMdThYvn
GC content47.39%
Information content (bits; total / per base)13.129 / 0.938
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8589

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (16) 0.605 0.713 0.447 0.537 0.564 0.721 1.342 1.92 14.062 43.013
Mouse 3 (18) 0.693 0.785 0.538 0.623 0.647 0.735 1.626 1.942 79.293 151.319

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.979 0.968 0.905 0.893 0.76 0.772
best 0.997 0.996 0.984 0.974 0.963 0.949
Methyl HT-SELEX, 2 experiments median 0.993 0.989 0.978 0.971 0.896 0.897
best 0.997 0.996 0.984 0.974 0.963 0.949
Non-Methyl HT-SELEX, 4 experiments median 0.953 0.933 0.824 0.823 0.674 0.7
best 0.986 0.982 0.941 0.917 0.814 0.811
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.1
HGNCHGNC:7775
MGIMGI:102469
EntrezGene (human)GeneID:4772
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NFAC1_HUMAN
UniProt ID (mouse)NFAC1_MOUSE
UniProt AC (human)O95644
(TFClass)
UniProt AC (mouse)O88942
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 3 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
012504.52476.51643.51964.5
024835.0179.03341.0234.0
033.06101.00.02485.0
040.00.08589.00.0
050.00.08589.00.0
068589.00.00.00.0
078589.00.00.00.0
085785.01787.0140.0877.0
092393.01021.01765.03410.0
10915.0400.0311.06963.0
11789.02641.0675.04484.0
12784.06243.0640.0922.0
131454.54231.51990.5912.5
142488.251569.252653.251878.25
PFM
ACGT
010.2920.2880.1910.229
020.5630.0210.3890.027
030.00.710.00.289
040.00.01.00.0
050.00.01.00.0
061.00.00.00.0
071.00.00.00.0
080.6740.2080.0160.102
090.2790.1190.2050.397
100.1070.0470.0360.811
110.0920.3070.0790.522
120.0910.7270.0750.107
130.1690.4930.2320.106
140.290.1830.3090.219
PWM
ACGT
010.1540.143-0.267-0.089
020.811-2.4730.442-2.208
03-6.0121.044-6.8560.146
04-6.856-6.8561.386-6.856
05-6.856-6.8561.386-6.856
061.386-6.856-6.856-6.856
071.386-6.856-6.856-6.856
080.99-0.183-2.715-0.894
090.108-0.742-0.1960.462
10-0.852-1.676-1.9261.176
11-0.9990.207-1.1550.736
12-1.0061.067-1.208-0.844
13-0.3890.678-0.076-0.854
140.147-0.3130.211-0.134
Standard thresholds
P-value Threshold
0.001 2.68581
0.0005 4.53451
0.0001 7.29736