MotifNFAC1.H12INVITRO.0.P.B
Gene (human)NFATC1
(GeneCards)
Gene synonyms (human)NFAT2, NFATC
Gene (mouse)Nfatc1
Gene synonyms (mouse)Nfat2, Nfatc
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length16
ConsensusWGGAARvdnTKWvWMW
GC content39.16%
Information content (bits; total / per base)13.663 / 0.854
Data sourcesChIP-Seq
Aligned words996

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (16) 0.58 0.791 0.478 0.723 0.606 0.797 1.794 2.995 22.204 83.602
Mouse 3 (18) 0.86 0.93 0.828 0.89 0.867 0.934 4.144 4.59 354.418 512.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.817 0.761 0.739 0.69 0.671 0.638
best 0.949 0.916 0.923 0.885 0.859 0.825
Methyl HT-SELEX, 2 experiments median 0.889 0.839 0.848 0.8 0.78 0.744
best 0.949 0.916 0.923 0.885 0.859 0.825
Non-Methyl HT-SELEX, 4 experiments median 0.784 0.734 0.694 0.659 0.615 0.606
best 0.913 0.871 0.844 0.803 0.729 0.715
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.1
HGNCHGNC:7775
MGIMGI:102469
EntrezGene (human)GeneID:4772
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NFAC1_HUMAN
UniProt ID (mouse)NFAC1_MOUSE
UniProt AC (human)O95644
(TFClass)
UniProt AC (mouse)O88942
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 3 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
01190.048.069.0689.0
0212.01.0980.03.0
036.02.0988.00.0
04941.018.035.02.0
05944.03.035.014.0
06791.062.081.062.0
07531.0173.0204.088.0
08411.068.0111.0406.0
09345.0227.0255.0169.0
1078.052.056.0810.0
1167.074.0670.0185.0
12732.056.092.0116.0
13147.0319.0443.087.0
14127.0112.077.0680.0
15174.0618.0111.093.0
16672.094.0107.0123.0
PFM
ACGT
010.1910.0480.0690.692
020.0120.0010.9840.003
030.0060.0020.9920.0
040.9450.0180.0350.002
050.9480.0030.0350.014
060.7940.0620.0810.062
070.5330.1740.2050.088
080.4130.0680.1110.408
090.3460.2280.2560.17
100.0780.0520.0560.813
110.0670.0740.6730.186
120.7350.0560.0920.116
130.1480.320.4450.087
140.1280.1120.0770.683
150.1750.620.1110.093
160.6750.0940.1070.123
PWM
ACGT
01-0.268-1.618-1.2661.013
02-2.905-4.5221.365-3.971
03-3.48-4.2091.373-4.979
041.324-2.542-1.921-4.209
051.328-3.971-1.921-2.769
061.151-1.37-1.109-1.37
070.754-0.361-0.198-1.028
080.498-1.28-0.7990.486
090.324-0.0920.024-0.384
10-1.146-1.54-1.4691.175
11-1.294-1.1970.985-0.295
121.074-1.469-0.984-0.756
13-0.5220.2460.573-1.039
14-0.667-0.791-1.1581.0
15-0.3550.905-0.799-0.973
160.988-0.963-0.836-0.698
Standard thresholds
P-value Threshold
0.001 3.69256
0.0005 4.74306
0.0001 6.90876