MotifNFAC1.H12CORE.2.SM.B
Gene (human)NFATC1
(GeneCards)
Gene synonyms (human)NFAT2, NFATC
Gene (mouse)Nfatc1
Gene synonyms (mouse)Nfat2, Nfatc
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
B
Motif length20
ConsensusdWWhYbnbhACGGAAAMWdn
GC content38.31%
Information content (bits; total / per base)16.419 / 0.821
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9292

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (16) 0.601 0.733 0.456 0.605 0.588 0.726 1.515 2.198 16.234 39.444
Mouse 3 (18) 0.713 0.812 0.582 0.674 0.678 0.778 1.963 2.378 110.838 189.229

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.956 0.938 0.881 0.863 0.735 0.749
best 1.0 1.0 0.998 0.997 0.963 0.962
Methyl HT-SELEX, 2 experiments median 0.991 0.988 0.97 0.963 0.881 0.885
best 1.0 1.0 0.998 0.997 0.963 0.962
Non-Methyl HT-SELEX, 4 experiments median 0.894 0.872 0.745 0.744 0.626 0.648
best 0.994 0.993 0.949 0.942 0.789 0.807
TF superclassImmunoglobulin fold {6} (TFClass)
TF classRel homology region (RHR) factors {6.1} (TFClass)
TF familyNFAT-related {6.1.3} (TFClass)
TF subfamily {6.1.3.0} (TFClass)
TFClass IDTFClass: 6.1.3.0.1
HGNCHGNC:7775
MGIMGI:102469
EntrezGene (human)GeneID:4772
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)NFAC1_HUMAN
UniProt ID (mouse)NFAC1_MOUSE
UniProt AC (human)O95644
(TFClass)
UniProt AC (mouse)O88942
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 3 mouse
HT-SELEX 4
Methyl-HT-SELEX 2
PCM
ACGT
011615.01298.01638.04741.0
021150.0985.0984.06173.0
031015.0610.0746.06921.0
04764.03334.0620.04574.0
05656.05879.0500.02257.0
061655.03692.02225.01720.0
071706.02194.02410.02982.0
081282.03357.01298.03355.0
093513.01756.0793.03230.0
106997.019.02136.0140.0
111.06046.00.03245.0
120.00.09292.00.0
130.00.09292.00.0
149292.00.00.00.0
159291.01.00.00.0
169111.0164.01.016.0
175803.01952.0924.0613.0
183199.0390.0179.05524.0
193272.751054.751732.753231.75
202394.01946.01749.03203.0
PFM
ACGT
010.1740.140.1760.51
020.1240.1060.1060.664
030.1090.0660.080.745
040.0820.3590.0670.492
050.0710.6330.0540.243
060.1780.3970.2390.185
070.1840.2360.2590.321
080.1380.3610.140.361
090.3780.1890.0850.348
100.7530.0020.230.015
110.00.6510.00.349
120.00.01.00.0
130.00.01.00.0
141.00.00.00.0
151.00.00.00.0
160.9810.0180.00.002
170.6250.210.0990.066
180.3440.0420.0190.594
190.3520.1140.1860.348
200.2580.2090.1880.345
PWM
ACGT
01-0.363-0.581-0.3490.713
02-0.702-0.857-0.8580.977
03-0.827-1.334-1.1341.091
04-1.110.361-1.3180.677
05-1.2620.928-1.532-0.029
06-0.3390.463-0.043-0.3
07-0.308-0.0570.0370.25
08-0.5940.368-0.5810.367
090.413-0.28-1.0730.329
101.102-4.694-0.084-2.794
11-6.5620.956-6.9260.334
12-6.926-6.9261.386-6.926
13-6.926-6.9261.386-6.926
141.386-6.926-6.926-6.926
151.385-6.562-6.926-6.926
161.366-2.638-6.562-4.846
170.915-0.174-0.92-1.33
180.32-1.78-2.5520.866
190.342-0.788-0.2930.33
200.03-0.177-0.2830.321
Standard thresholds
P-value Threshold
0.001 -0.08944
0.0005 1.72521
0.0001 5.72481