MotifNF2L2.H12INVIVO.0.P.B
Gene (human)NFE2L2
(GeneCards)
Gene synonyms (human)NRF2
Gene (mouse)Nfe2l2
Gene synonyms (mouse)Nrf2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length15
ConsensusGCYRWSTCAYnvYbv
GC content52.13%
Information content (bits; total / per base)12.974 / 0.865
Data sourcesChIP-Seq
Aligned words472

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 8 (51) 0.95 0.986 0.917 0.974 0.943 0.982 5.535 6.126 429.921 929.357
Mouse 10 (69) 0.876 0.988 0.849 0.985 0.878 0.986 4.531 6.818 155.658 548.959
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyJun-related {1.1.1} (TFClass)
TF subfamilyNFE2 {1.1.1.2} (TFClass)
TFClass IDTFClass: 1.1.1.2.3
HGNCHGNC:7782
MGIMGI:108420
EntrezGene (human)GeneID:4780
(SSTAR profile)
EntrezGene (mouse)GeneID:18024
(SSTAR profile)
UniProt ID (human)NF2L2_HUMAN
UniProt ID (mouse)NF2L2_MOUSE
UniProt AC (human)Q16236
(TFClass)
UniProt AC (mouse)Q60795
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 8 human, 10 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
0120.024.0396.032.0
024.0432.028.08.0
0349.0100.05.0318.0
0473.048.0292.059.0
05360.017.021.074.0
0623.075.0361.013.0
070.03.04.0465.0
0813.0458.00.01.0
09463.02.01.06.0
106.0180.033.0253.0
1179.089.0158.0146.0
1280.0165.0163.064.0
1346.084.045.0297.0
1453.085.0263.071.0
15242.073.086.071.0
PFM
ACGT
010.0420.0510.8390.068
020.0080.9150.0590.017
030.1040.2120.0110.674
040.1550.1020.6190.125
050.7630.0360.0440.157
060.0490.1590.7650.028
070.00.0060.0080.985
080.0280.970.00.002
090.9810.0040.0020.013
100.0130.3810.070.536
110.1670.1890.3350.309
120.1690.350.3450.136
130.0970.1780.0950.629
140.1120.180.5570.15
150.5130.1550.1820.15
PWM
ACGT
01-1.714-1.5431.202-1.271
02-3.0721.288-1.398-2.528
03-0.861-0.163-2.9060.983
04-0.472-0.8810.898-0.68
051.107-1.864-1.668-0.459
06-1.583-0.4461.109-2.107
07-4.352-3.271-3.0721.362
08-2.1071.347-4.352-3.852
091.357-3.52-3.852-2.764
10-2.7640.418-1.2420.756
11-0.395-0.2780.2890.21
12-0.3830.3320.32-0.601
13-0.922-0.335-0.9430.915
14-0.785-0.3230.794-0.5
150.712-0.472-0.312-0.5
Standard thresholds
P-value Threshold
0.001 3.94506
0.0005 4.96786
0.0001 7.07036