NF2L2.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NF2L2.H12INVITRO.0.P.D
Gene (human)	NFE2L2 (GeneCards)
Gene synonyms (human)	NRF2
Gene (mouse)	Nfe2l2
Gene synonyms (mouse)	Nrf2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	15
Consensus	GCYRWSTCAYnvYbv
GC content	52.13%
Information content (bits; total / per base)	12.974 / 0.865
Data sources	ChIP-Seq
Aligned words	472

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (51)	0.95	0.986	0.917	0.974	0.943	0.982	5.535	6.126	429.921	929.357
Mouse	10 (69)	0.876	0.988	0.849	0.985	0.878	0.986	4.531	6.818	155.658	548.959

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.3
HGNC	HGNC:7782
MGI	MGI:108420
EntrezGene (human)	GeneID:4780 (SSTAR profile)
EntrezGene (mouse)	GeneID:18024 (SSTAR profile)
UniProt ID (human)	NF2L2_HUMAN
UniProt ID (mouse)	NF2L2_MOUSE
UniProt AC (human)	Q16236 (TFClass)
UniProt AC (mouse)	Q60795 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 10 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	NF2L2.H12INVITRO.0.P.D.pcm
PWM	NF2L2.H12INVITRO.0.P.D.pwm
PFM	NF2L2.H12INVITRO.0.P.D.pfm
Alignment	NF2L2.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	NF2L2.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	NF2L2.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	NF2L2.H12INVITRO.0.P.D_meme_format.meme
Transfac format	NF2L2.H12INVITRO.0.P.D_transfac_format.txt
Homer format	NF2L2.H12INVITRO.0.P.D_homer_format_0.001.txt NF2L2.H12INVITRO.0.P.D_homer_format_0.0005.txt NF2L2.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	20.0	24.0	396.0	32.0
02	4.0	432.0	28.0	8.0
03	49.0	100.0	5.0	318.0
04	73.0	48.0	292.0	59.0
05	360.0	17.0	21.0	74.0
06	23.0	75.0	361.0	13.0
07	0.0	3.0	4.0	465.0
08	13.0	458.0	0.0	1.0
09	463.0	2.0	1.0	6.0
10	6.0	180.0	33.0	253.0
11	79.0	89.0	158.0	146.0
12	80.0	165.0	163.0	64.0
13	46.0	84.0	45.0	297.0
14	53.0	85.0	263.0	71.0
15	242.0	73.0	86.0	71.0

PFM

	A	C	G	T
01	0.042	0.051	0.839	0.068
02	0.008	0.915	0.059	0.017
03	0.104	0.212	0.011	0.674
04	0.155	0.102	0.619	0.125
05	0.763	0.036	0.044	0.157
06	0.049	0.159	0.765	0.028
07	0.0	0.006	0.008	0.985
08	0.028	0.97	0.0	0.002
09	0.981	0.004	0.002	0.013
10	0.013	0.381	0.07	0.536
11	0.167	0.189	0.335	0.309
12	0.169	0.35	0.345	0.136
13	0.097	0.178	0.095	0.629
14	0.112	0.18	0.557	0.15
15	0.513	0.155	0.182	0.15

PWM

	A	C	G	T
01	-1.714	-1.543	1.202	-1.271
02	-3.072	1.288	-1.398	-2.528
03	-0.861	-0.163	-2.906	0.983
04	-0.472	-0.881	0.898	-0.68
05	1.107	-1.864	-1.668	-0.459
06	-1.583	-0.446	1.109	-2.107
07	-4.352	-3.271	-3.072	1.362
08	-2.107	1.347	-4.352	-3.852
09	1.357	-3.52	-3.852	-2.764
10	-2.764	0.418	-1.242	0.756
11	-0.395	-0.278	0.289	0.21
12	-0.383	0.332	0.32	-0.601
13	-0.922	-0.335	-0.943	0.915
14	-0.785	-0.323	0.794	-0.5
15	0.712	-0.472	-0.312	-0.5

Standard thresholds

P-value	Threshold
0.001	3.94506
0.0005	4.96786
0.0001	7.07036