NF2L2.H12CORE.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NF2L2.H12CORE.1.P.B
Gene (human)	NFE2L2 (GeneCards)
Gene synonyms (human)	NRF2
Gene (mouse)	Nfe2l2
Gene synonyms (mouse)	Nrf2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	15
Consensus	dWWhTGCTGAGTCAT
GC content	41.8%
Information content (bits; total / per base)	18.812 / 1.254
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	8 (51)	0.951	0.992	0.927	0.989	0.945	0.991	6.426	8.751	427.328	1010.745
Mouse	10 (69)	0.882	0.981	0.851	0.977	0.873	0.98	4.721	7.371	159.538	562.678

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.3
HGNC	HGNC:7782
MGI	MGI:108420
EntrezGene (human)	GeneID:4780 (SSTAR profile)
EntrezGene (mouse)	GeneID:18024 (SSTAR profile)
UniProt ID (human)	NF2L2_HUMAN
UniProt ID (mouse)	NF2L2_MOUSE
UniProt AC (human)	Q16236 (TFClass)
UniProt AC (mouse)	Q60795 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	8 human, 10 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	NF2L2.H12CORE.1.P.B.pcm
PWM	NF2L2.H12CORE.1.P.B.pwm
PFM	NF2L2.H12CORE.1.P.B.pfm
Alignment	NF2L2.H12CORE.1.P.B.words.tsv
Threshold to P-value map	NF2L2.H12CORE.1.P.B.thr
Motif in other formats
JASPAR format	NF2L2.H12CORE.1.P.B_jaspar_format.txt
MEME format	NF2L2.H12CORE.1.P.B_meme_format.meme
Transfac format	NF2L2.H12CORE.1.P.B_transfac_format.txt
Homer format	NF2L2.H12CORE.1.P.B_homer_format_0.001.txt NF2L2.H12CORE.1.P.B_homer_format_0.0005.txt NF2L2.H12CORE.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	470.0	73.0	251.0	206.0
02	582.0	57.0	83.0	278.0
03	504.0	94.0	57.0	345.0
04	200.0	249.0	155.0	396.0
05	48.0	55.0	15.0	882.0
06	7.0	19.0	971.0	3.0
07	28.0	963.0	3.0	6.0
08	41.0	43.0	6.0	910.0
09	29.0	22.0	906.0	43.0
10	945.0	15.0	2.0	38.0
11	18.0	87.0	883.0	12.0
12	1.0	1.0	0.0	998.0
13	6.0	988.0	6.0	0.0
14	1000.0	0.0	0.0	0.0
15	4.0	248.0	18.0	730.0

PFM

	A	C	G	T
01	0.47	0.073	0.251	0.206
02	0.582	0.057	0.083	0.278
03	0.504	0.094	0.057	0.345
04	0.2	0.249	0.155	0.396
05	0.048	0.055	0.015	0.882
06	0.007	0.019	0.971	0.003
07	0.028	0.963	0.003	0.006
08	0.041	0.043	0.006	0.91
09	0.029	0.022	0.906	0.043
10	0.945	0.015	0.002	0.038
11	0.018	0.087	0.883	0.012
12	0.001	0.001	0.0	0.998
13	0.006	0.988	0.006	0.0
14	1.0	0.0	0.0	0.0
15	0.004	0.248	0.018	0.73

PWM

	A	C	G	T
01	0.628	-1.215	0.004	-0.192
02	0.841	-1.455	-1.089	0.105
03	0.698	-0.967	-1.455	0.32
04	-0.221	-0.004	-0.474	0.457
05	-1.622	-1.49	-2.711	1.256
06	-3.362	-2.497	1.352	-3.975
07	-2.136	1.344	-3.975	-3.484
08	-1.774	-1.728	-3.484	1.287
09	-2.103	-2.362	1.283	-1.728
10	1.325	-2.711	-4.213	-1.846
11	-2.546	-1.043	1.257	-2.909
12	-4.525	-4.525	-4.982	1.379
13	-3.484	1.369	-3.484	-4.982
14	1.381	-4.982	-4.982	-4.982
15	-3.783	-0.008	-2.546	1.067

Standard thresholds

P-value	Threshold
0.001	0.47216
0.0005	1.93761
0.0001	5.02231