NF2L1.H12INVITRO.0.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	NF2L1.H12INVITRO.0.P.D
Gene (human)	NFE2L1 (GeneCards)
Gene synonyms (human)	HBZ17, NRF1, TCF11
Gene (mouse)	Nfe2l1
Gene synonyms (mouse)	Nrf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	16
Consensus	ddWWhTGCTGAGTCAT
GC content	40.65%
Information content (bits; total / per base)	19.776 / 1.236
Data sources	ChIP-Seq
Aligned words	929

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.711	0.978	0.672	0.973	0.775	0.977	4.244	8.812	36.77	851.097
Mouse	1 (7)	0.927	0.937	0.911	0.922	0.945	0.955	5.486	5.567	522.721	595.252

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Jun-related {1.1.1} (TFClass)
TF subfamily	NFE2 {1.1.1.2} (TFClass)
TFClass ID	TFClass: 1.1.1.2.2
HGNC	HGNC:7781
MGI	MGI:99421
EntrezGene (human)	GeneID:4779 (SSTAR profile)
EntrezGene (mouse)	GeneID:18023 (SSTAR profile)
UniProt ID (human)	NF2L1_HUMAN
UniProt ID (mouse)	NF2L1_MOUSE
UniProt AC (human)	Q14494 (TFClass)
UniProt AC (mouse)	Q61985 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	NF2L1.H12INVITRO.0.P.D.pcm
PWM	NF2L1.H12INVITRO.0.P.D.pwm
PFM	NF2L1.H12INVITRO.0.P.D.pfm
Alignment	NF2L1.H12INVITRO.0.P.D.words.tsv
Threshold to P-value map	NF2L1.H12INVITRO.0.P.D.thr
Motif in other formats
JASPAR format	NF2L1.H12INVITRO.0.P.D_jaspar_format.txt
MEME format	NF2L1.H12INVITRO.0.P.D_meme_format.meme
Transfac format	NF2L1.H12INVITRO.0.P.D_transfac_format.txt
Homer format	NF2L1.H12INVITRO.0.P.D_homer_format_0.001.txt NF2L1.H12INVITRO.0.P.D_homer_format_0.0005.txt NF2L1.H12INVITRO.0.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	421.0	95.0	269.0	144.0
02	458.0	47.0	245.0	179.0
03	589.0	33.0	59.0	248.0
04	499.0	95.0	41.0	294.0
05	195.0	204.0	138.0	392.0
06	53.0	41.0	11.0	824.0
07	0.0	4.0	918.0	7.0
08	37.0	880.0	1.0	11.0
09	28.0	21.0	1.0	879.0
10	23.0	16.0	844.0	46.0
11	862.0	8.0	0.0	59.0
12	9.0	90.0	827.0	3.0
13	2.0	0.0	2.0	925.0
14	0.0	926.0	3.0	0.0
15	924.0	2.0	1.0	2.0
16	1.0	219.0	1.0	708.0

PFM

	A	C	G	T
01	0.453	0.102	0.29	0.155
02	0.493	0.051	0.264	0.193
03	0.634	0.036	0.064	0.267
04	0.537	0.102	0.044	0.316
05	0.21	0.22	0.149	0.422
06	0.057	0.044	0.012	0.887
07	0.0	0.004	0.988	0.008
08	0.04	0.947	0.001	0.012
09	0.03	0.023	0.001	0.946
10	0.025	0.017	0.909	0.05
11	0.928	0.009	0.0	0.064
12	0.01	0.097	0.89	0.003
13	0.002	0.0	0.002	0.996
14	0.0	0.997	0.003	0.0
15	0.995	0.002	0.001	0.002
16	0.001	0.236	0.001	0.762

PWM

	A	C	G	T
01	0.592	-0.883	0.146	-0.474
02	0.675	-1.569	0.053	-0.258
03	0.926	-1.908	-1.349	0.065
04	0.761	-0.883	-1.701	0.234
05	-0.173	-0.129	-0.516	0.52
06	-1.453	-1.701	-2.913	1.261
07	-4.92	-3.713	1.369	-3.291
08	-1.799	1.327	-4.459	-2.913
09	-2.064	-2.332	-4.459	1.326
10	-2.248	-2.581	1.285	-1.59
11	1.306	-3.182	-4.92	-1.349
12	-3.084	-0.937	1.265	-3.906
13	-4.145	-4.92	-4.145	1.376
14	-4.92	1.378	-3.906	-4.92
15	1.375	-4.145	-4.459	-4.145
16	-4.459	-0.058	-4.459	1.11

Standard thresholds

P-value	Threshold
0.001	-0.35914
0.0005	1.19286
0.0001	4.46221