MotifNANOG.H12INVITRO.1.P.B
Gene (human)NANOG
(GeneCards)
Gene synonyms (human)
Gene (mouse)Nanog
Gene synonyms (mouse)Ecat4, Enk
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length11
ConsensusnbTRATGGSYb
GC content47.44%
Information content (bits; total / per base)9.285 / 0.844
Data sourcesChIP-Seq
Aligned words500

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 15 (95) 0.666 0.709 0.489 0.531 0.579 0.631 1.284 1.463 20.276 53.62
Mouse 25 (160) 0.688 0.802 0.534 0.64 0.607 0.713 1.43 1.799 35.921 86.481

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Methyl HT-SELEX, 1 experiments median 0.725 0.651 0.701 0.635 0.656 0.61
best 0.725 0.651 0.701 0.635 0.656 0.61

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 0.609 0.689 -0.041 0.019
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNANOG {3.1.2.12} (TFClass)
TFClass IDTFClass: 3.1.2.12.1
HGNCHGNC:20857
MGIMGI:1919200
EntrezGene (human)GeneID:79923
(SSTAR profile)
EntrezGene (mouse)GeneID:71950
(SSTAR profile)
UniProt ID (human)NANOG_HUMAN
UniProt ID (mouse)NANOG_MOUSE
UniProt AC (human)Q9H9S0
(TFClass)
UniProt AC (mouse)Q80Z64
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 15 human, 25 mouse
HT-SELEX 0
Methyl-HT-SELEX 1
PCM
ACGT
0171.0164.0163.0102.0
0242.0145.086.0227.0
0367.09.022.0402.0
04182.05.0313.00.0
05481.08.02.09.0
0612.03.07.0478.0
076.03.0370.0121.0
0848.07.0432.013.0
0927.0287.0113.073.0
1022.0157.019.0302.0
1143.0166.0128.0163.0
PFM
ACGT
010.1420.3280.3260.204
020.0840.290.1720.454
030.1340.0180.0440.804
040.3640.010.6260.0
050.9620.0160.0040.018
060.0240.0060.0140.956
070.0120.0060.740.242
080.0960.0140.8640.026
090.0540.5740.2260.146
100.0440.3140.0380.604
110.0860.3320.2560.326
PWM
ACGT
01-0.5560.2690.263-0.201
02-1.0670.147-0.3680.591
03-0.613-2.484-1.6811.16
040.372-2.9610.91-4.4
051.338-2.584-3.573-2.484
06-2.234-3.325-2.6941.332
07-2.819-3.3251.077-0.032
08-0.938-2.6941.231-2.163
09-1.4890.824-0.1-0.529
10-1.6810.225-1.8180.875
11-1.0440.2810.0230.263
Standard thresholds
P-value Threshold
0.001 4.92017
0.0005 5.739355
0.0001 7.379345