Motif | NANOG.H12CORE.0.P.B |
Gene (human) | NANOG (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Nanog |
Gene synonyms (mouse) | Ecat4, Enk |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | NANOG.H12CORE.0.P.B |
Gene (human) | NANOG (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Nanog |
Gene synonyms (mouse) | Ecat4, Enk |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 17 |
Consensus | nbYWTTSWnWTGYWRWd |
GC content | 35.59% |
Information content (bits; total / per base) | 11.886 / 0.699 |
Data sources | ChIP-Seq |
Aligned words | 999 |
ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
---|---|---|---|---|---|---|---|---|---|---|---|
Human | 15 (95) | 0.804 | 0.855 | 0.732 | 0.783 | 0.853 | 0.895 | 3.481 | 3.837 | 105.456 | 150.187 |
Mouse | 25 (160) | 0.766 | 0.857 | 0.692 | 0.797 | 0.782 | 0.866 | 3.0 | 3.724 | 80.261 | 183.886 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Methyl HT-SELEX, 1 experiments | median | 0.517 | 0.514 | 0.492 | 0.502 | 0.481 | 0.496 |
best | 0.517 | 0.514 | 0.492 | 0.502 | 0.481 | 0.496 |
rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
---|---|---|---|---|
# | 11.214 | 7.201 | 0.24 | 0.269 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | NK-related {3.1.2} (TFClass) |
TF subfamily | NANOG {3.1.2.12} (TFClass) |
TFClass ID | TFClass: 3.1.2.12.1 |
HGNC | HGNC:20857 |
MGI | MGI:1919200 |
EntrezGene (human) | GeneID:79923 (SSTAR profile) |
EntrezGene (mouse) | GeneID:71950 (SSTAR profile) |
UniProt ID (human) | NANOG_HUMAN |
UniProt ID (mouse) | NANOG_MOUSE |
UniProt AC (human) | Q9H9S0 (TFClass) |
UniProt AC (mouse) | Q80Z64 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 15 human, 25 mouse |
HT-SELEX | 0 |
Methyl-HT-SELEX | 1 |
PCM | NANOG.H12CORE.0.P.B.pcm |
PWM | NANOG.H12CORE.0.P.B.pwm |
PFM | NANOG.H12CORE.0.P.B.pfm |
Alignment | NANOG.H12CORE.0.P.B.words.tsv |
Threshold to P-value map | NANOG.H12CORE.0.P.B.thr |
Motif in other formats | |
JASPAR format | NANOG.H12CORE.0.P.B_jaspar_format.txt |
MEME format | NANOG.H12CORE.0.P.B_meme_format.meme |
Transfac format | NANOG.H12CORE.0.P.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 129.0 | 241.0 | 308.0 | 321.0 |
02 | 36.0 | 516.0 | 205.0 | 242.0 |
03 | 83.0 | 541.0 | 64.0 | 311.0 |
04 | 345.0 | 54.0 | 51.0 | 549.0 |
05 | 18.0 | 61.0 | 45.0 | 875.0 |
06 | 62.0 | 9.0 | 31.0 | 897.0 |
07 | 79.0 | 287.0 | 583.0 | 50.0 |
08 | 386.0 | 26.0 | 31.0 | 556.0 |
09 | 211.0 | 254.0 | 201.0 | 333.0 |
10 | 755.0 | 36.0 | 70.0 | 138.0 |
11 | 76.0 | 12.0 | 54.0 | 857.0 |
12 | 15.0 | 21.0 | 812.0 | 151.0 |
13 | 36.0 | 613.0 | 116.0 | 234.0 |
14 | 679.0 | 19.0 | 13.0 | 288.0 |
15 | 623.0 | 62.0 | 264.0 | 50.0 |
16 | 791.0 | 56.0 | 60.0 | 92.0 |
17 | 131.0 | 126.0 | 202.0 | 540.0 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.129 | 0.241 | 0.308 | 0.321 |
02 | 0.036 | 0.517 | 0.205 | 0.242 |
03 | 0.083 | 0.542 | 0.064 | 0.311 |
04 | 0.345 | 0.054 | 0.051 | 0.55 |
05 | 0.018 | 0.061 | 0.045 | 0.876 |
06 | 0.062 | 0.009 | 0.031 | 0.898 |
07 | 0.079 | 0.287 | 0.584 | 0.05 |
08 | 0.386 | 0.026 | 0.031 | 0.557 |
09 | 0.211 | 0.254 | 0.201 | 0.333 |
10 | 0.756 | 0.036 | 0.07 | 0.138 |
11 | 0.076 | 0.012 | 0.054 | 0.858 |
12 | 0.015 | 0.021 | 0.813 | 0.151 |
13 | 0.036 | 0.614 | 0.116 | 0.234 |
14 | 0.68 | 0.019 | 0.013 | 0.288 |
15 | 0.624 | 0.062 | 0.264 | 0.05 |
16 | 0.792 | 0.056 | 0.06 | 0.092 |
17 | 0.131 | 0.126 | 0.202 | 0.541 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.654 | -0.035 | 0.208 | 0.249 |
02 | -1.897 | 0.722 | -0.196 | -0.031 |
03 | -1.088 | 0.769 | -1.342 | 0.218 |
04 | 0.321 | -1.507 | -1.562 | 0.784 |
05 | -2.545 | -1.389 | -1.683 | 1.249 |
06 | -1.373 | -3.155 | -2.039 | 1.274 |
07 | -1.136 | 0.138 | 0.844 | -1.581 |
08 | 0.433 | -2.205 | -2.039 | 0.797 |
09 | -0.167 | 0.017 | -0.215 | 0.286 |
10 | 1.102 | -1.897 | -1.254 | -0.588 |
11 | -1.174 | -2.908 | -1.507 | 1.228 |
12 | -2.71 | -2.404 | 1.174 | -0.499 |
13 | -1.897 | 0.894 | -0.759 | -0.065 |
14 | 0.996 | -2.496 | -2.838 | 0.142 |
15 | 0.91 | -1.373 | 0.055 | -1.581 |
16 | 1.148 | -1.472 | -1.405 | -0.987 |
17 | -0.639 | -0.677 | -0.211 | 0.767 |
P-value | Threshold |
---|---|
0.001 | 4.27696 |
0.0005 | 5.17741 |
0.0001 | 7.06651 |