MotifNANOG.H12CORE.0.P.B
Gene (human)NANOG
(GeneCards)
Gene synonyms (human)
Gene (mouse)Nanog
Gene synonyms (mouse)Ecat4, Enk
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length17
ConsensusnbYWTTSWnWTGYWRWd
GC content35.59%
Information content (bits; total / per base)11.886 / 0.699
Data sourcesChIP-Seq
Aligned words999

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 15 (95) 0.804 0.855 0.732 0.783 0.853 0.895 3.481 3.837 105.456 150.187
Mouse 25 (160) 0.766 0.857 0.692 0.797 0.782 0.866 3.0 3.724 80.261 183.886

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Methyl HT-SELEX, 1 experiments median 0.517 0.514 0.492 0.502 0.481 0.496
best 0.517 0.514 0.492 0.502 0.481 0.496

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 11.214 7.201 0.24 0.269
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyNANOG {3.1.2.12} (TFClass)
TFClass IDTFClass: 3.1.2.12.1
HGNCHGNC:20857
MGIMGI:1919200
EntrezGene (human)GeneID:79923
(SSTAR profile)
EntrezGene (mouse)GeneID:71950
(SSTAR profile)
UniProt ID (human)NANOG_HUMAN
UniProt ID (mouse)NANOG_MOUSE
UniProt AC (human)Q9H9S0
(TFClass)
UniProt AC (mouse)Q80Z64
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 15 human, 25 mouse
HT-SELEX 0
Methyl-HT-SELEX 1
PCM
ACGT
01129.0241.0308.0321.0
0236.0516.0205.0242.0
0383.0541.064.0311.0
04345.054.051.0549.0
0518.061.045.0875.0
0662.09.031.0897.0
0779.0287.0583.050.0
08386.026.031.0556.0
09211.0254.0201.0333.0
10755.036.070.0138.0
1176.012.054.0857.0
1215.021.0812.0151.0
1336.0613.0116.0234.0
14679.019.013.0288.0
15623.062.0264.050.0
16791.056.060.092.0
17131.0126.0202.0540.0
PFM
ACGT
010.1290.2410.3080.321
020.0360.5170.2050.242
030.0830.5420.0640.311
040.3450.0540.0510.55
050.0180.0610.0450.876
060.0620.0090.0310.898
070.0790.2870.5840.05
080.3860.0260.0310.557
090.2110.2540.2010.333
100.7560.0360.070.138
110.0760.0120.0540.858
120.0150.0210.8130.151
130.0360.6140.1160.234
140.680.0190.0130.288
150.6240.0620.2640.05
160.7920.0560.060.092
170.1310.1260.2020.541
PWM
ACGT
01-0.654-0.0350.2080.249
02-1.8970.722-0.196-0.031
03-1.0880.769-1.3420.218
040.321-1.507-1.5620.784
05-2.545-1.389-1.6831.249
06-1.373-3.155-2.0391.274
07-1.1360.1380.844-1.581
080.433-2.205-2.0390.797
09-0.1670.017-0.2150.286
101.102-1.897-1.254-0.588
11-1.174-2.908-1.5071.228
12-2.71-2.4041.174-0.499
13-1.8970.894-0.759-0.065
140.996-2.496-2.8380.142
150.91-1.3730.055-1.581
161.148-1.472-1.405-0.987
17-0.639-0.677-0.2110.767
Standard thresholds
P-value Threshold
0.001 4.27696
0.0005 5.17741
0.0001 7.06651