MYF6.H12INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYF6.H12INVIVO.0.SM.D
Gene (human)	MYF6 (GeneCards)
Gene synonyms (human)	BHLHC4, MRF4
Gene (mouse)	Myf6
Gene synonyms (mouse)	Mrf4, Myf-6
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	14
Consensus	nRhCASCTGWCvbn
GC content	54.19%
Information content (bits; total / per base)	13.459 / 0.961
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9975

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.815	0.808	0.779	0.774	0.732	0.73
Overall, 4 experiments	best	0.997	0.995	0.993	0.989	0.972	0.966
Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.993	0.989	0.972	0.966
Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.993	0.989	0.972	0.966
Non-Methyl HT-SELEX, 3 experiments	median	0.638	0.627	0.576	0.573	0.54	0.544
Non-Methyl HT-SELEX, 3 experiments	best	0.993	0.988	0.983	0.975	0.924	0.915

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.932	0.764	0.928	0.71

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	MyoD-ASC-related {1.2.2} (TFClass)
TF subfamily	Myogenic TFs {1.2.2.1} (TFClass)
TFClass ID	TFClass: 1.2.2.1.4
HGNC	HGNC:7566
MGI	MGI:97253
EntrezGene (human)	GeneID:4618 (SSTAR profile)
EntrezGene (mouse)	GeneID:17878 (SSTAR profile)
UniProt ID (human)	MYF6_HUMAN
UniProt ID (mouse)	MYF6_MOUSE
UniProt AC (human)	P23409 (TFClass)
UniProt AC (mouse)	P15375 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	MYF6.H12INVIVO.0.SM.D.pcm
PWM	MYF6.H12INVIVO.0.SM.D.pwm
PFM	MYF6.H12INVIVO.0.SM.D.pfm
Alignment	MYF6.H12INVIVO.0.SM.D.words.tsv
Threshold to P-value map	MYF6.H12INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	MYF6.H12INVIVO.0.SM.D_jaspar_format.txt
MEME format	MYF6.H12INVIVO.0.SM.D_meme_format.meme
Transfac format	MYF6.H12INVIVO.0.SM.D_transfac_format.txt
Homer format	MYF6.H12INVIVO.0.SM.D_homer_format_0.001.txt MYF6.H12INVIVO.0.SM.D_homer_format_0.0005.txt MYF6.H12INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1643.25	3397.25	2488.25	2446.25
02	5047.75	818.75	3665.75	442.75
03	5629.0	1210.0	1191.0	1945.0
04	16.0	9896.0	16.0	47.0
05	9891.0	6.0	65.0	13.0
06	1010.0	3525.0	5423.0	17.0
07	67.0	9821.0	81.0	6.0
08	3.0	0.0	0.0	9972.0
09	3.0	0.0	9972.0	0.0
10	4521.0	159.0	36.0	5259.0
11	19.0	6321.0	27.0	3608.0
12	3414.0	1856.0	4026.0	679.0
13	1617.75	4337.75	1656.75	2362.75
14	2160.75	2856.75	2827.75	2129.75

PFM

	A	C	G	T
01	0.165	0.341	0.249	0.245
02	0.506	0.082	0.367	0.044
03	0.564	0.121	0.119	0.195
04	0.002	0.992	0.002	0.005
05	0.992	0.001	0.007	0.001
06	0.101	0.353	0.544	0.002
07	0.007	0.985	0.008	0.001
08	0.0	0.0	0.0	1.0
09	0.0	0.0	1.0	0.0
10	0.453	0.016	0.004	0.527
11	0.002	0.634	0.003	0.362
12	0.342	0.186	0.404	0.068
13	0.162	0.435	0.166	0.237
14	0.217	0.286	0.283	0.214

PWM

	A	C	G	T
01	-0.417	0.309	-0.002	-0.019
02	0.705	-1.112	0.385	-1.724
03	0.814	-0.722	-0.738	-0.248
04	-4.915	1.378	-4.915	-3.925
05	1.377	-5.706	-3.613	-5.094
06	-0.902	0.346	0.776	-4.862
07	-3.584	1.37	-3.4	-5.706
08	-6.154	-6.989	-6.989	1.385
09	-6.154	-6.989	1.385	-6.989
10	0.595	-2.739	-4.177	0.746
11	-4.764	0.93	-4.445	0.369
12	0.314	-0.295	0.479	-1.298
13	-0.432	0.553	-0.408	-0.054
14	-0.143	0.136	0.126	-0.158

Standard thresholds

P-value	Threshold
0.001	2.28436
0.0005	3.62806
0.0001	7.15266