MYF6.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYF6.H12INVITRO.0.SM.B
Gene (human)	MYF6 (GeneCards)
Gene synonyms (human)	BHLHC4, MRF4
Gene (mouse)	Myf6
Gene synonyms (mouse)	Mrf4, Myf-6
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	nRhCASCTGWYvnn
GC content	52.28%
Information content (bits; total / per base)	13.304 / 0.95
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9866

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.816	0.809	0.781	0.776	0.733	0.731
Overall, 4 experiments	best	0.997	0.995	0.994	0.991	0.975	0.969
Methyl HT-SELEX, 1 experiments	median	0.997	0.995	0.994	0.991	0.975	0.969
Methyl HT-SELEX, 1 experiments	best	0.997	0.995	0.994	0.991	0.975	0.969
Non-Methyl HT-SELEX, 3 experiments	median	0.639	0.631	0.578	0.575	0.542	0.545
Non-Methyl HT-SELEX, 3 experiments	best	0.993	0.988	0.984	0.977	0.925	0.916

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.92	0.775	0.927	0.711

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	MyoD-ASC-related {1.2.2} (TFClass)
TF subfamily	Myogenic TFs {1.2.2.1} (TFClass)
TFClass ID	TFClass: 1.2.2.1.4
HGNC	HGNC:7566
MGI	MGI:97253
EntrezGene (human)	GeneID:4618 (SSTAR profile)
EntrezGene (mouse)	GeneID:17878 (SSTAR profile)
UniProt ID (human)	MYF6_HUMAN
UniProt ID (mouse)	MYF6_MOUSE
UniProt AC (human)	P23409 (TFClass)
UniProt AC (mouse)	P15375 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	MYF6.H12INVITRO.0.SM.B.pcm
PWM	MYF6.H12INVITRO.0.SM.B.pwm
PFM	MYF6.H12INVITRO.0.SM.B.pfm
Alignment	MYF6.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	MYF6.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	MYF6.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	MYF6.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	MYF6.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	MYF6.H12INVITRO.0.SM.B_homer_format_0.001.txt MYF6.H12INVITRO.0.SM.B_homer_format_0.0005.txt MYF6.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1634.5	3251.5	2455.5	2524.5
02	5382.5	787.5	3353.5	342.5
03	5982.0	1390.0	1238.0	1256.0
04	26.0	9778.0	25.0	37.0
05	9787.0	16.0	29.0	34.0
06	2209.0	3095.0	4514.0	48.0
07	130.0	9723.0	6.0	7.0
08	1.0	0.0	0.0	9865.0
09	3.0	0.0	9862.0	1.0
10	3167.0	289.0	27.0	6383.0
11	20.0	5240.0	44.0	4562.0
12	3576.0	2444.0	2964.0	882.0
13	1481.75	4464.75	1481.75	2437.75
14	2113.25	3315.25	2412.25	2025.25

PFM

	A	C	G	T
01	0.166	0.33	0.249	0.256
02	0.546	0.08	0.34	0.035
03	0.606	0.141	0.125	0.127
04	0.003	0.991	0.003	0.004
05	0.992	0.002	0.003	0.003
06	0.224	0.314	0.458	0.005
07	0.013	0.986	0.001	0.001
08	0.0	0.0	0.0	1.0
09	0.0	0.0	1.0	0.0
10	0.321	0.029	0.003	0.647
11	0.002	0.531	0.004	0.462
12	0.362	0.248	0.3	0.089
13	0.15	0.453	0.15	0.247
14	0.214	0.336	0.245	0.205

PWM

	A	C	G	T
01	-0.411	0.276	-0.004	0.023
02	0.78	-1.14	0.307	-1.969
03	0.885	-0.573	-0.688	-0.674
04	-4.469	1.377	-4.505	-4.14
05	1.378	-4.905	-4.368	-4.22
06	-0.11	0.227	0.604	-3.893
07	-2.926	1.371	-5.695	-5.582
08	-6.618	-6.979	-6.979	1.385
09	-6.144	-6.979	1.385	-6.618
10	0.25	-2.137	-4.434	0.95
11	-4.707	0.753	-3.976	0.615
12	0.371	-0.009	0.184	-1.027
13	-0.509	0.593	-0.509	-0.012
14	-0.154	0.295	-0.022	-0.197

Standard thresholds

P-value	Threshold
0.001	2.39076
0.0005	3.70561
0.0001	7.291465