MYC.H12RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYC.H12RSNP.0.P.B
Gene (human)	MYC (GeneCards)
Gene synonyms (human)	BHLHE39
Gene (mouse)	Myc
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	vvSCACGYGSb
GC content	67.54%
Information content (bits; total / per base)	10.918 / 0.993
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	113 (715)	0.862	0.944	0.766	0.889	0.796	0.909	2.582	3.511	159.131	375.108
Mouse	79 (488)	0.87	0.953	0.767	0.897	0.805	0.918	2.557	3.28	134.903	490.796

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	100.0	7.543	0.268	0.185

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MYC {1.2.6.5} (TFClass)
TFClass ID	TFClass: 1.2.6.5.1
HGNC	HGNC:7553
MGI	MGI:97250
EntrezGene (human)	GeneID:4609 (SSTAR profile)
EntrezGene (mouse)	GeneID:17869 (SSTAR profile)
UniProt ID (human)	MYC_HUMAN
UniProt ID (mouse)	MYC_MOUSE
UniProt AC (human)	P01106 (TFClass)
UniProt AC (mouse)	P01108 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	113 human, 79 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	MYC.H12RSNP.0.P.B.pcm
PWM	MYC.H12RSNP.0.P.B.pwm
PFM	MYC.H12RSNP.0.P.B.pfm
Alignment	MYC.H12RSNP.0.P.B.words.tsv
Threshold to P-value map	MYC.H12RSNP.0.P.B.thr
Motif in other formats
JASPAR format	MYC.H12RSNP.0.P.B_jaspar_format.txt
MEME format	MYC.H12RSNP.0.P.B_meme_format.meme
Transfac format	MYC.H12RSNP.0.P.B_transfac_format.txt
Homer format	MYC.H12RSNP.0.P.B_homer_format_0.001.txt MYC.H12RSNP.0.P.B_homer_format_0.0005.txt MYC.H12RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	234.0	263.0	370.0	133.0
02	221.0	184.0	413.0	182.0
03	182.0	591.0	223.0	4.0
04	19.0	979.0	0.0	2.0
05	991.0	5.0	0.0	4.0
06	3.0	713.0	5.0	279.0
07	0.0	7.0	988.0	5.0
08	83.0	241.0	2.0	674.0
09	4.0	4.0	978.0	14.0
10	42.0	506.0	434.0	18.0
11	111.0	293.0	230.0	366.0

PFM

	A	C	G	T
01	0.234	0.263	0.37	0.133
02	0.221	0.184	0.413	0.182
03	0.182	0.591	0.223	0.004
04	0.019	0.979	0.0	0.002
05	0.991	0.005	0.0	0.004
06	0.003	0.713	0.005	0.279
07	0.0	0.007	0.988	0.005
08	0.083	0.241	0.002	0.674
09	0.004	0.004	0.978	0.014
10	0.042	0.506	0.434	0.018
11	0.111	0.293	0.23	0.366

PWM

	A	C	G	T
01	-0.066	0.05	0.39	-0.625
02	-0.122	-0.304	0.499	-0.315
03	-0.315	0.856	-0.113	-3.783
04	-2.497	1.36	-4.982	-4.213
05	1.372	-3.622	-4.982	-3.783
06	-3.975	1.044	-3.622	0.109
07	-4.982	-3.362	1.369	-3.622
08	-1.089	-0.036	-4.213	0.987
09	-3.783	-3.783	1.359	-2.773
10	-1.75	0.702	0.549	-2.546
11	-0.803	0.158	-0.083	0.379

Standard thresholds

P-value	Threshold
0.001	4.14245
0.0005	5.486535
0.0001	7.780125