MYC.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYC.H12INVIVO.0.P.B
Gene (human)	MYC (GeneCards)
Gene synonyms (human)	BHLHE39
Gene (mouse)	Myc
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	dMCACGTGSdb
GC content	67.14%
Information content (bits; total / per base)	10.771 / 0.979
Data sources	ChIP-Seq
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	113 (715)	0.868	0.947	0.771	0.887	0.8	0.918	2.746	3.713	162.469	381.215
Mouse	79 (488)	0.876	0.96	0.778	0.912	0.813	0.938	2.754	3.538	134.641	484.125

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	100.0	6.776	0.224	0.176

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MYC {1.2.6.5} (TFClass)
TFClass ID	TFClass: 1.2.6.5.1
HGNC	HGNC:7553
MGI	MGI:97250
EntrezGene (human)	GeneID:4609 (SSTAR profile)
EntrezGene (mouse)	GeneID:17869 (SSTAR profile)
UniProt ID (human)	MYC_HUMAN
UniProt ID (mouse)	MYC_MOUSE
UniProt AC (human)	P01106 (TFClass)
UniProt AC (mouse)	P01108 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	113 human, 79 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	MYC.H12INVIVO.0.P.B.pcm
PWM	MYC.H12INVIVO.0.P.B.pwm
PFM	MYC.H12INVIVO.0.P.B.pfm
Alignment	MYC.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	MYC.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	MYC.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	MYC.H12INVIVO.0.P.B_meme_format.meme
Transfac format	MYC.H12INVIVO.0.P.B_transfac_format.txt
Homer format	MYC.H12INVIVO.0.P.B_homer_format_0.001.txt MYC.H12INVIVO.0.P.B_homer_format_0.0005.txt MYC.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	165.0	138.0	530.0	164.0
02	151.0	711.0	90.0	45.0
03	44.0	949.0	3.0	1.0
04	807.0	6.0	114.0	70.0
05	6.0	802.0	4.0	185.0
06	9.0	11.0	971.0	6.0
07	18.0	90.0	14.0	875.0
08	2.0	10.0	974.0	11.0
09	22.0	518.0	341.0	116.0
10	129.0	124.0	303.0	441.0
11	109.0	435.0	225.0	228.0

PFM

	A	C	G	T
01	0.165	0.138	0.532	0.164
02	0.151	0.713	0.09	0.045
03	0.044	0.952	0.003	0.001
04	0.809	0.006	0.114	0.07
05	0.006	0.804	0.004	0.186
06	0.009	0.011	0.974	0.006
07	0.018	0.09	0.014	0.878
08	0.002	0.01	0.977	0.011
09	0.022	0.52	0.342	0.116
10	0.129	0.124	0.304	0.442
11	0.109	0.436	0.226	0.229

PWM

	A	C	G	T
01	-0.409	-0.586	0.751	-0.415
02	-0.497	1.044	-1.007	-1.681
03	-1.703	1.332	-3.972	-4.522
04	1.17	-3.481	-0.774	-1.253
05	-3.481	1.164	-3.78	-0.296
06	-3.153	-2.982	1.355	-3.481
07	-2.543	-1.007	-2.77	1.251
08	-4.21	-3.064	1.358	-2.982
09	-2.359	0.728	0.312	-0.757
10	-0.652	-0.691	0.194	0.568
11	-0.818	0.554	-0.102	-0.088

Standard thresholds

P-value	Threshold
0.001	4.53373
0.0005	5.50165
0.0001	7.4055