MYC.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYC.H12CORE.0.P.B
Gene (human)	MYC (GeneCards)
Gene synonyms (human)	BHLHE39
Gene (mouse)	Myc
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	10
Consensus	vvCACGYGSh
GC content	66.89%
Information content (bits; total / per base)	10.301 / 1.03
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	113 (715)	0.867	0.941	0.774	0.886	0.801	0.917	2.626	3.478	161.959	380.377
Mouse	79 (488)	0.874	0.948	0.774	0.893	0.811	0.912	2.578	3.217	138.433	474.26

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	100.0	7.335	0.269	0.178

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MYC {1.2.6.5} (TFClass)
TFClass ID	TFClass: 1.2.6.5.1
HGNC	HGNC:7553
MGI	MGI:97250
EntrezGene (human)	GeneID:4609 (SSTAR profile)
EntrezGene (mouse)	GeneID:17869 (SSTAR profile)
UniProt ID (human)	MYC_HUMAN
UniProt ID (mouse)	MYC_MOUSE
UniProt AC (human)	P01106 (TFClass)
UniProt AC (mouse)	P01108 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	113 human, 79 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	MYC.H12CORE.0.P.B.pcm
PWM	MYC.H12CORE.0.P.B.pwm
PFM	MYC.H12CORE.0.P.B.pfm
Alignment	MYC.H12CORE.0.P.B.words.tsv
Threshold to P-value map	MYC.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	MYC.H12CORE.0.P.B_jaspar_format.txt
MEME format	MYC.H12CORE.0.P.B_meme_format.meme
Transfac format	MYC.H12CORE.0.P.B_transfac_format.txt
Homer format	MYC.H12CORE.0.P.B_homer_format_0.001.txt MYC.H12CORE.0.P.B_homer_format_0.0005.txt MYC.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	294.0	340.0	242.0	124.0
02	268.0	375.0	291.0	66.0
03	24.0	974.0	2.0	0.0
04	989.0	1.0	4.0	6.0
05	4.0	780.0	9.0	207.0
06	14.0	10.0	974.0	2.0
07	68.0	245.0	2.0	685.0
08	2.0	17.0	930.0	51.0
09	27.0	238.0	708.0	27.0
10	174.0	380.0	167.0	279.0

PFM

	A	C	G	T
01	0.294	0.34	0.242	0.124
02	0.268	0.375	0.291	0.066
03	0.024	0.974	0.002	0.0
04	0.989	0.001	0.004	0.006
05	0.004	0.78	0.009	0.207
06	0.014	0.01	0.974	0.002
07	0.068	0.245	0.002	0.685
08	0.002	0.017	0.93	0.051
09	0.027	0.238	0.708	0.027
10	0.174	0.38	0.167	0.279

PWM

	A	C	G	T
01	0.161	0.306	-0.032	-0.694
02	0.069	0.403	0.151	-1.313
03	-2.281	1.355	-4.213	-4.982
04	1.37	-4.525	-3.783	-3.484
05	-3.783	1.133	-3.156	-0.187
06	-2.773	-3.066	1.355	-4.213
07	-1.284	-0.02	-4.213	1.004
08	-4.213	-2.598	1.309	-1.563
09	-2.171	-0.049	1.037	-2.171
10	-0.359	0.416	-0.4	0.109

Standard thresholds

P-value	Threshold
0.001	4.58916
0.0005	5.641855
0.0001	7.661175