MYBA.H12INVIVO.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYBA.H12INVIVO.2.S.B
Gene (human)	MYBL1 (GeneCards)
Gene synonyms (human)	AMYB
Gene (mouse)	Mybl1
Gene synonyms (mouse)	Amyb
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	17
Consensus	nhRRCMGTTAACbKbhn
GC content	46.38%
Information content (bits; total / per base)	17.064 / 1.004
Data sources	HT-SELEX
Aligned words	1421

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.748	0.772	0.646	0.673	0.593	0.653	1.5	1.756	4.398	6.009
Mouse	2 (14)	0.782	0.809	0.661	0.692	0.672	0.714	1.818	1.959	37.476	48.114

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.925	0.905	0.843	0.825	0.736	0.734
Non-Methyl HT-SELEX, 2 experiments	best	0.982	0.975	0.94	0.925	0.83	0.823

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Myb/SANT domain {3.5.1} (TFClass)
TF subfamily	Myb-like {3.5.1.1} (TFClass)
TFClass ID	TFClass: 3.5.1.1.2
HGNC	HGNC:7547
MGI	MGI:99925
EntrezGene (human)	GeneID:4603 (SSTAR profile)
EntrezGene (mouse)	GeneID:17864 (SSTAR profile)
UniProt ID (human)	MYBA_HUMAN
UniProt ID (mouse)	MYBA_MOUSE
UniProt AC (human)	P10243 (TFClass)
UniProt AC (mouse)	P51960 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MYBA.H12INVIVO.2.S.B.pcm
PWM	MYBA.H12INVIVO.2.S.B.pwm
PFM	MYBA.H12INVIVO.2.S.B.pfm
Alignment	MYBA.H12INVIVO.2.S.B.words.tsv
Threshold to P-value map	MYBA.H12INVIVO.2.S.B.thr
Motif in other formats
JASPAR format	MYBA.H12INVIVO.2.S.B_jaspar_format.txt
MEME format	MYBA.H12INVIVO.2.S.B_meme_format.meme
Transfac format	MYBA.H12INVIVO.2.S.B_transfac_format.txt
Homer format	MYBA.H12INVIVO.2.S.B_homer_format_0.001.txt MYBA.H12INVIVO.2.S.B_homer_format_0.0005.txt MYBA.H12INVIVO.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	535.5	268.5	240.5	376.5
02	218.0	307.0	131.0	765.0
03	666.0	2.0	714.0	39.0
04	812.0	0.0	554.0	55.0
05	0.0	1421.0	0.0	0.0
06	572.0	698.0	149.0	2.0
07	0.0	0.0	1421.0	0.0
08	0.0	0.0	0.0	1421.0
09	0.0	0.0	0.0	1421.0
10	1364.0	0.0	57.0	0.0
11	1396.0	0.0	16.0	9.0
12	231.0	1160.0	6.0	24.0
13	77.0	439.0	715.0	190.0
14	84.0	72.0	1112.0	153.0
15	264.0	311.0	270.0	576.0
16	280.25	355.25	127.25	658.25
17	323.0	307.0	351.0	440.0

PFM

	A	C	G	T
01	0.377	0.189	0.169	0.265
02	0.153	0.216	0.092	0.538
03	0.469	0.001	0.502	0.027
04	0.571	0.0	0.39	0.039
05	0.0	1.0	0.0	0.0
06	0.403	0.491	0.105	0.001
07	0.0	0.0	1.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	0.0	1.0
10	0.96	0.0	0.04	0.0
11	0.982	0.0	0.011	0.006
12	0.163	0.816	0.004	0.017
13	0.054	0.309	0.503	0.134
14	0.059	0.051	0.783	0.108
15	0.186	0.219	0.19	0.405
16	0.197	0.25	0.09	0.463
17	0.227	0.216	0.247	0.31

PWM

	A	C	G	T
01	0.409	-0.278	-0.388	0.058
02	-0.485	-0.145	-0.989	0.764
03	0.626	-4.539	0.696	-2.169
04	0.824	-5.282	0.443	-1.838
05	-5.282	1.382	-5.282	-5.282
06	0.474	0.673	-0.862	-4.539
07	-5.282	-5.282	1.382	-5.282
08	-5.282	-5.282	-5.282	1.382
09	-5.282	-5.282	-5.282	1.382
10	1.342	-5.282	-1.804	-5.282
11	1.365	-5.282	-2.998	-3.497
12	-0.428	1.18	-3.822	-2.627
13	-1.511	0.211	0.697	-0.621
14	-1.426	-1.576	1.138	-0.836
15	-0.295	-0.132	-0.273	0.481
16	-0.236	0.0	-1.018	0.614
17	-0.095	-0.145	-0.012	0.213

Standard thresholds

P-value	Threshold
0.001	0.21441
0.0005	1.89111
0.0001	5.26081