MYBA.H12INVIVO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYBA.H12INVIVO.0.P.B
Gene (human)	MYBL1 (GeneCards)
Gene synonyms (human)	AMYB
Gene (mouse)	Mybl1
Gene synonyms (mouse)	Amyb
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	vbbGRCvGTTRvnvv
GC content	59.93%
Information content (bits; total / per base)	11.494 / 0.766
Data sources	ChIP-Seq
Aligned words	996

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.765	0.831	0.709	0.755	0.699	0.767	2.213	2.447	13.041	19.097
Mouse	2 (14)	0.898	0.929	0.819	0.878	0.843	0.875	3.973	4.306	187.146	300.495

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.899	0.854	0.84	0.801	0.751	0.73
Non-Methyl HT-SELEX, 2 experiments	best	0.955	0.923	0.925	0.889	0.838	0.813

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Myb/SANT domain {3.5.1} (TFClass)
TF subfamily	Myb-like {3.5.1.1} (TFClass)
TFClass ID	TFClass: 3.5.1.1.2
HGNC	HGNC:7547
MGI	MGI:99925
EntrezGene (human)	GeneID:4603 (SSTAR profile)
EntrezGene (mouse)	GeneID:17864 (SSTAR profile)
UniProt ID (human)	MYBA_HUMAN
UniProt ID (mouse)	MYBA_MOUSE
UniProt AC (human)	P10243 (TFClass)
UniProt AC (mouse)	P51960 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MYBA.H12INVIVO.0.P.B.pcm
PWM	MYBA.H12INVIVO.0.P.B.pwm
PFM	MYBA.H12INVIVO.0.P.B.pfm
Alignment	MYBA.H12INVIVO.0.P.B.words.tsv
Threshold to P-value map	MYBA.H12INVIVO.0.P.B.thr
Motif in other formats
JASPAR format	MYBA.H12INVIVO.0.P.B_jaspar_format.txt
MEME format	MYBA.H12INVIVO.0.P.B_meme_format.meme
Transfac format	MYBA.H12INVIVO.0.P.B_transfac_format.txt
Homer format	MYBA.H12INVIVO.0.P.B_homer_format_0.001.txt MYBA.H12INVIVO.0.P.B_homer_format_0.0005.txt MYBA.H12INVIVO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	361.0	187.0	322.0	126.0
02	103.0	202.0	586.0	105.0
03	128.0	288.0	146.0	434.0
04	128.0	38.0	792.0	38.0
05	216.0	21.0	717.0	42.0
06	19.0	956.0	14.0	7.0
07	423.0	291.0	264.0	18.0
08	2.0	5.0	985.0	4.0
09	2.0	7.0	8.0	979.0
10	3.0	2.0	5.0	986.0
11	317.0	29.0	542.0	108.0
12	168.0	329.0	463.0	36.0
13	348.0	250.0	245.0	153.0
14	186.0	215.0	496.0	99.0
15	325.0	213.0	336.0	122.0

PFM

	A	C	G	T
01	0.362	0.188	0.323	0.127
02	0.103	0.203	0.588	0.105
03	0.129	0.289	0.147	0.436
04	0.129	0.038	0.795	0.038
05	0.217	0.021	0.72	0.042
06	0.019	0.96	0.014	0.007
07	0.425	0.292	0.265	0.018
08	0.002	0.005	0.989	0.004
09	0.002	0.007	0.008	0.983
10	0.003	0.002	0.005	0.99
11	0.318	0.029	0.544	0.108
12	0.169	0.33	0.465	0.036
13	0.349	0.251	0.246	0.154
14	0.187	0.216	0.498	0.099
15	0.326	0.214	0.337	0.122

PWM

	A	C	G	T
01	0.369	-0.284	0.256	-0.674
02	-0.873	-0.208	0.852	-0.854
03	-0.659	0.145	-0.529	0.553
04	-0.659	-1.842	1.152	-1.842
05	-0.141	-2.401	1.053	-1.746
06	-2.493	1.34	-2.769	-3.358
07	0.527	0.155	0.058	-2.542
08	-4.209	-3.618	1.37	-3.779
09	-4.209	-3.358	-3.25	1.364
10	-3.971	-4.209	-3.618	1.371
11	0.24	-2.099	0.774	-0.826
12	-0.39	0.277	0.617	-1.894
13	0.333	0.004	-0.016	-0.483
14	-0.289	-0.146	0.686	-0.912
15	0.265	-0.155	0.298	-0.706

Standard thresholds

P-value	Threshold
0.001	4.27831
0.0005	5.31666
0.0001	7.39206