MYBA.H12INVITRO.1.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYBA.H12INVITRO.1.PS.A
Gene (human)	MYBL1 (GeneCards)
Gene synonyms (human)	AMYB
Gene (mouse)	Mybl1
Gene synonyms (mouse)	Amyb
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	11
Consensus	nddCMGTTRdn
GC content	44.97%
Information content (bits; total / per base)	9.418 / 0.856
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9356

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.823	0.862	0.716	0.78	0.727	0.773	1.899	2.145	11.222	14.509
Mouse	2 (14)	0.865	0.885	0.75	0.777	0.791	0.826	2.121	2.302	181.794	268.31

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.951	0.93	0.897	0.875	0.798	0.791
Non-Methyl HT-SELEX, 2 experiments	best	0.988	0.981	0.969	0.956	0.899	0.887

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Myb/SANT domain {3.5.1} (TFClass)
TF subfamily	Myb-like {3.5.1.1} (TFClass)
TFClass ID	TFClass: 3.5.1.1.2
HGNC	HGNC:7547
MGI	MGI:99925
EntrezGene (human)	GeneID:4603 (SSTAR profile)
EntrezGene (mouse)	GeneID:17864 (SSTAR profile)
UniProt ID (human)	MYBA_HUMAN
UniProt ID (mouse)	MYBA_MOUSE
UniProt AC (human)	P10243 (TFClass)
UniProt AC (mouse)	P51960 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MYBA.H12INVITRO.1.PS.A.pcm
PWM	MYBA.H12INVITRO.1.PS.A.pwm
PFM	MYBA.H12INVITRO.1.PS.A.pfm
Alignment	MYBA.H12INVITRO.1.PS.A.words.tsv
Threshold to P-value map	MYBA.H12INVITRO.1.PS.A.thr
Motif in other formats
JASPAR format	MYBA.H12INVITRO.1.PS.A_jaspar_format.txt
MEME format	MYBA.H12INVITRO.1.PS.A_meme_format.meme
Transfac format	MYBA.H12INVITRO.1.PS.A_transfac_format.txt
Homer format	MYBA.H12INVITRO.1.PS.A_homer_format_0.001.txt MYBA.H12INVITRO.1.PS.A_homer_format_0.0005.txt MYBA.H12INVITRO.1.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2545.5	1954.5	1924.5	2931.5
02	3364.0	978.0	3055.0	1959.0
03	4546.0	386.0	2514.0	1910.0
04	185.0	8880.0	113.0	178.0
05	2765.0	4751.0	1815.0	25.0
06	0.0	0.0	9356.0	0.0
07	0.0	0.0	0.0	9356.0
08	0.0	0.0	0.0	9356.0
09	5642.0	421.0	2569.0	724.0
10	4580.25	1244.25	2164.25	1367.25
11	3060.0	2422.0	1735.0	2139.0

PFM

	A	C	G	T
01	0.272	0.209	0.206	0.313
02	0.36	0.105	0.327	0.209
03	0.486	0.041	0.269	0.204
04	0.02	0.949	0.012	0.019
05	0.296	0.508	0.194	0.003
06	0.0	0.0	1.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.603	0.045	0.275	0.077
10	0.49	0.133	0.231	0.146
11	0.327	0.259	0.185	0.229

PWM

	A	C	G	T
01	0.085	-0.179	-0.195	0.226
02	0.363	-0.871	0.267	-0.177
03	0.664	-1.797	0.072	-0.202
04	-2.526	1.333	-3.011	-2.564
05	0.167	0.708	-0.253	-4.452
06	-6.932	-6.932	1.386	-6.932
07	-6.932	-6.932	-6.932	1.386
08	-6.932	-6.932	-6.932	1.386
09	0.88	-1.71	0.094	-1.171
10	0.672	-0.63	-0.078	-0.536
11	0.268	0.035	-0.298	-0.089

Standard thresholds

P-value	Threshold
0.001	5.347825
0.0005	6.2318
0.0001	7.44923