MYBA.H12INVITRO.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYBA.H12INVITRO.0.P.B
Gene (human)	MYBL1 (GeneCards)
Gene synonyms (human)	AMYB
Gene (mouse)	Mybl1
Gene synonyms (mouse)	Amyb
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	16
Consensus	vbhRRCvGTTRvnvvb
GC content	57.55%
Information content (bits; total / per base)	11.395 / 0.712
Data sources	ChIP-Seq
Aligned words	982

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.778	0.826	0.723	0.744	0.71	0.765	2.09	2.442	12.013	16.77
Mouse	2 (14)	0.9	0.924	0.823	0.876	0.849	0.875	4.195	4.586	186.568	321.721

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.908	0.864	0.849	0.812	0.756	0.738
Non-Methyl HT-SELEX, 2 experiments	best	0.959	0.931	0.934	0.901	0.847	0.824

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Myb/SANT domain {3.5.1} (TFClass)
TF subfamily	Myb-like {3.5.1.1} (TFClass)
TFClass ID	TFClass: 3.5.1.1.2
HGNC	HGNC:7547
MGI	MGI:99925
EntrezGene (human)	GeneID:4603 (SSTAR profile)
EntrezGene (mouse)	GeneID:17864 (SSTAR profile)
UniProt ID (human)	MYBA_HUMAN
UniProt ID (mouse)	MYBA_MOUSE
UniProt AC (human)	P10243 (TFClass)
UniProt AC (mouse)	P51960 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MYBA.H12INVITRO.0.P.B.pcm
PWM	MYBA.H12INVITRO.0.P.B.pwm
PFM	MYBA.H12INVITRO.0.P.B.pfm
Alignment	MYBA.H12INVITRO.0.P.B.words.tsv
Threshold to P-value map	MYBA.H12INVITRO.0.P.B.thr
Motif in other formats
JASPAR format	MYBA.H12INVITRO.0.P.B_jaspar_format.txt
MEME format	MYBA.H12INVITRO.0.P.B_meme_format.meme
Transfac format	MYBA.H12INVITRO.0.P.B_transfac_format.txt
Homer format	MYBA.H12INVITRO.0.P.B_homer_format_0.001.txt MYBA.H12INVITRO.0.P.B_homer_format_0.0005.txt MYBA.H12INVITRO.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	396.0	166.0	290.0	130.0
02	130.0	163.0	550.0	139.0
03	138.0	242.0	124.0	478.0
04	132.0	16.0	756.0	78.0
05	234.0	16.0	641.0	91.0
06	10.0	947.0	10.0	15.0
07	471.0	254.0	237.0	20.0
08	2.0	2.0	975.0	3.0
09	3.0	8.0	9.0	962.0
10	3.0	4.0	4.0	971.0
11	349.0	13.0	523.0	97.0
12	182.0	285.0	458.0	57.0
13	352.0	230.0	234.0	166.0
14	192.0	222.0	463.0	105.0
15	343.0	209.0	301.0	129.0
16	127.0	253.0	437.0	165.0

PFM

	A	C	G	T
01	0.403	0.169	0.295	0.132
02	0.132	0.166	0.56	0.142
03	0.141	0.246	0.126	0.487
04	0.134	0.016	0.77	0.079
05	0.238	0.016	0.653	0.093
06	0.01	0.964	0.01	0.015
07	0.48	0.259	0.241	0.02
08	0.002	0.002	0.993	0.003
09	0.003	0.008	0.009	0.98
10	0.003	0.004	0.004	0.989
11	0.355	0.013	0.533	0.099
12	0.185	0.29	0.466	0.058
13	0.358	0.234	0.238	0.169
14	0.196	0.226	0.471	0.107
15	0.349	0.213	0.307	0.131
16	0.129	0.258	0.445	0.168

PWM

	A	C	G	T
01	0.475	-0.388	0.166	-0.63
02	-0.63	-0.406	0.803	-0.563
03	-0.571	-0.014	-0.676	0.663
04	-0.615	-2.635	1.12	-1.132
05	-0.048	-2.635	0.955	-0.981
06	-3.049	1.345	-3.049	-2.694
07	0.648	0.034	-0.035	-2.432
08	-4.196	-4.196	1.374	-3.958
09	-3.958	-3.236	-3.138	1.361
10	-3.958	-3.766	-3.766	1.37
11	0.35	-2.821	0.753	-0.918
12	-0.297	0.148	0.62	-1.437
13	0.358	-0.065	-0.048	-0.388
14	-0.244	-0.1	0.631	-0.84
15	0.332	-0.16	0.203	-0.637
16	-0.653	0.03	0.574	-0.394

Standard thresholds

P-value	Threshold
0.001	4.31136
0.0005	5.37141
0.0001	7.42071