MYBA.H12CORE.2.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYBA.H12CORE.2.S.B
Gene (human)	MYBL1 (GeneCards)
Gene synonyms (human)	AMYB
Gene (mouse)	Mybl1
Gene synonyms (mouse)	Amyb
LOGO
LOGO (reverse complement)
Motif subtype	2
Quality	B

Motif length	14
Consensus	ndRCMGTTAACbvn
GC content	46.82%
Information content (bits; total / per base)	15.302 / 1.093
Data sources	HT-SELEX
Aligned words	588

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.786	0.812	0.639	0.703	0.567	0.643	1.377	1.769	3.42	4.602
Mouse	2 (14)	0.811	0.832	0.634	0.664	0.584	0.614	1.418	1.505	28.387	37.509

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.936	0.916	0.867	0.846	0.768	0.761
Non-Methyl HT-SELEX, 2 experiments	best	0.985	0.979	0.953	0.938	0.866	0.853

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Myb/SANT domain {3.5.1} (TFClass)
TF subfamily	Myb-like {3.5.1.1} (TFClass)
TFClass ID	TFClass: 3.5.1.1.2
HGNC	HGNC:7547
MGI	MGI:99925
EntrezGene (human)	GeneID:4603 (SSTAR profile)
EntrezGene (mouse)	GeneID:17864 (SSTAR profile)
UniProt ID (human)	MYBA_HUMAN
UniProt ID (mouse)	MYBA_MOUSE
UniProt AC (human)	P10243 (TFClass)
UniProt AC (mouse)	P51960 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MYBA.H12CORE.2.S.B.pcm
PWM	MYBA.H12CORE.2.S.B.pwm
PFM	MYBA.H12CORE.2.S.B.pfm
Alignment	MYBA.H12CORE.2.S.B.words.tsv
Threshold to P-value map	MYBA.H12CORE.2.S.B.thr
Motif in other formats
JASPAR format	MYBA.H12CORE.2.S.B_jaspar_format.txt
MEME format	MYBA.H12CORE.2.S.B_meme_format.meme
Transfac format	MYBA.H12CORE.2.S.B_transfac_format.txt
Homer format	MYBA.H12CORE.2.S.B_homer_format_0.001.txt MYBA.H12CORE.2.S.B_homer_format_0.0005.txt MYBA.H12CORE.2.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	160.75	137.75	120.75	168.75
02	285.25	50.25	149.25	103.25
03	410.0	2.0	103.0	73.0
04	0.0	588.0	0.0	0.0
05	87.0	430.0	71.0	0.0
06	0.0	0.0	588.0	0.0
07	0.0	0.0	0.0	588.0
08	0.0	0.0	0.0	588.0
09	586.0	0.0	2.0	0.0
10	568.0	1.0	7.0	12.0
11	89.0	479.0	4.0	16.0
12	68.0	154.0	266.0	100.0
13	89.5	91.5	323.5	83.5
14	147.5	163.5	122.5	154.5

PFM

	A	C	G	T
01	0.273	0.234	0.205	0.287
02	0.485	0.085	0.254	0.176
03	0.697	0.003	0.175	0.124
04	0.0	1.0	0.0	0.0
05	0.148	0.731	0.121	0.0
06	0.0	0.0	1.0	0.0
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.997	0.0	0.003	0.0
10	0.966	0.002	0.012	0.02
11	0.151	0.815	0.007	0.027
12	0.116	0.262	0.452	0.17
13	0.152	0.156	0.55	0.142
14	0.251	0.278	0.208	0.263

PWM

	A	C	G	T
01	0.088	-0.064	-0.194	0.137
02	0.658	-1.053	0.015	-0.349
03	1.019	-3.722	-0.351	-0.689
04	-4.535	1.378	-4.535	-4.535
05	-0.517	1.066	-0.716	-4.535
06	-4.535	-4.535	1.378	-4.535
07	-4.535	-4.535	-4.535	1.378
08	-4.535	-4.535	-4.535	1.378
09	1.375	-4.535	-3.722	-4.535
10	1.344	-4.048	-2.85	-2.392
11	-0.495	1.174	-3.279	-2.134
12	-0.759	0.046	0.588	-0.38
13	-0.489	-0.468	0.783	-0.557
14	0.003	0.105	-0.18	0.049

Standard thresholds

P-value	Threshold
0.001	2.04911
0.0005	3.48391
0.0001	6.256415