MYBA.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MYBA.H12CORE.0.P.B
Gene (human)	MYBL1 (GeneCards)
Gene synonyms (human)	AMYB
Gene (mouse)	Mybl1
Gene synonyms (mouse)	Amyb
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	15
Consensus	vvbRRCvGTTdvnvv
GC content	56.49%
Information content (bits; total / per base)	10.431 / 0.695
Data sources	ChIP-Seq
Aligned words	442

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (7)	0.78	0.834	0.716	0.755	0.711	0.763	2.2	2.461	10.469	14.301
Mouse	2 (14)	0.897	0.922	0.82	0.871	0.844	0.871	4.029	4.393	201.039	335.284

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.906	0.86	0.85	0.811	0.757	0.738
Non-Methyl HT-SELEX, 2 experiments	best	0.957	0.926	0.933	0.899	0.847	0.823

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Myb/SANT domain {3.5.1} (TFClass)
TF subfamily	Myb-like {3.5.1.1} (TFClass)
TFClass ID	TFClass: 3.5.1.1.2
HGNC	HGNC:7547
MGI	MGI:99925
EntrezGene (human)	GeneID:4603 (SSTAR profile)
EntrezGene (mouse)	GeneID:17864 (SSTAR profile)
UniProt ID (human)	MYBA_HUMAN
UniProt ID (mouse)	MYBA_MOUSE
UniProt AC (human)	P10243 (TFClass)
UniProt AC (mouse)	P51960 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MYBA.H12CORE.0.P.B.pcm
PWM	MYBA.H12CORE.0.P.B.pwm
PFM	MYBA.H12CORE.0.P.B.pfm
Alignment	MYBA.H12CORE.0.P.B.words.tsv
Threshold to P-value map	MYBA.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	MYBA.H12CORE.0.P.B_jaspar_format.txt
MEME format	MYBA.H12CORE.0.P.B_meme_format.meme
Transfac format	MYBA.H12CORE.0.P.B_transfac_format.txt
Homer format	MYBA.H12CORE.0.P.B_homer_format_0.001.txt MYBA.H12CORE.0.P.B_homer_format_0.0005.txt MYBA.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	179.0	62.0	149.0	52.0
02	67.0	82.0	241.0	52.0
03	64.0	118.0	65.0	195.0
04	60.0	19.0	320.0	43.0
05	118.0	7.0	274.0	43.0
06	8.0	423.0	9.0	2.0
07	173.0	124.0	125.0	20.0
08	2.0	3.0	433.0	4.0
09	3.0	4.0	1.0	434.0
10	1.0	0.0	4.0	437.0
11	158.0	12.0	203.0	69.0
12	86.0	133.0	187.0	36.0
13	154.0	94.0	115.0	79.0
14	82.0	94.0	204.0	62.0
15	154.0	108.0	132.0	48.0

PFM

	A	C	G	T
01	0.405	0.14	0.337	0.118
02	0.152	0.186	0.545	0.118
03	0.145	0.267	0.147	0.441
04	0.136	0.043	0.724	0.097
05	0.267	0.016	0.62	0.097
06	0.018	0.957	0.02	0.005
07	0.391	0.281	0.283	0.045
08	0.005	0.007	0.98	0.009
09	0.007	0.009	0.002	0.982
10	0.002	0.0	0.009	0.989
11	0.357	0.027	0.459	0.156
12	0.195	0.301	0.423	0.081
13	0.348	0.213	0.26	0.179
14	0.186	0.213	0.462	0.14
15	0.348	0.244	0.299	0.109

PWM

	A	C	G	T
01	0.477	-0.567	0.295	-0.739
02	-0.492	-0.294	0.772	-0.739
03	-0.536	0.065	-0.521	0.562
04	-0.599	-1.697	1.054	-0.923
05	0.065	-2.576	0.9	-0.923
06	-2.465	1.332	-2.365	-3.459
07	0.443	0.114	0.122	-1.65
08	-3.459	-3.21	1.356	-3.01
09	-3.21	-3.01	-3.793	1.358
10	-3.793	-4.298	-3.01	1.365
11	0.353	-2.114	0.602	-0.463
12	-0.247	0.183	0.521	-1.094
13	0.328	-0.159	0.039	-0.33
14	-0.294	-0.159	0.607	-0.567
15	0.328	-0.023	0.176	-0.816

Standard thresholds

P-value	Threshold
0.001	4.71211
0.0005	5.66576
0.0001	7.43761