MXI1.H12CORE.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MXI1.H12CORE.0.P.B
Gene (human)	MXI1 (GeneCards)
Gene synonyms (human)	BHLHC11
Gene (mouse)	Mxi1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	hvCACGTGKbn
GC content	62.37%
Information content (bits; total / per base)	10.614 / 0.965
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.823	0.84	0.743	0.762	0.755	0.775	2.626	2.735	199.228	247.721
Mouse	2 (13)	0.857	0.913	0.774	0.871	0.816	0.876	2.984	3.506	237.745	385.18

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	4.983	2.159	0.153	0.037

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MAD {1.2.6.7} (TFClass)
TFClass ID	TFClass: 1.2.6.7.5
HGNC	HGNC:7534
MGI	MGI:97245
EntrezGene (human)	GeneID:4601 (SSTAR profile)
EntrezGene (mouse)	GeneID:17859 (SSTAR profile)
UniProt ID (human)	MXI1_HUMAN
UniProt ID (mouse)	MXI1_MOUSE
UniProt AC (human)	P50539 (TFClass)
UniProt AC (mouse)	P50540 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 2 mouse
HT-SELEX	0
Methyl-HT-SELEX	0

PCM	MXI1.H12CORE.0.P.B.pcm
PWM	MXI1.H12CORE.0.P.B.pwm
PFM	MXI1.H12CORE.0.P.B.pfm
Alignment	MXI1.H12CORE.0.P.B.words.tsv
Threshold to P-value map	MXI1.H12CORE.0.P.B.thr
Motif in other formats
JASPAR format	MXI1.H12CORE.0.P.B_jaspar_format.txt
MEME format	MXI1.H12CORE.0.P.B_meme_format.meme
Transfac format	MXI1.H12CORE.0.P.B_transfac_format.txt
Homer format	MXI1.H12CORE.0.P.B_homer_format_0.001.txt MXI1.H12CORE.0.P.B_homer_format_0.0005.txt MXI1.H12CORE.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	395.0	256.0	81.0	268.0
02	202.0	291.0	478.0	29.0
03	15.0	967.0	16.0	2.0
04	932.0	12.0	45.0	11.0
05	9.0	944.0	8.0	39.0
06	98.0	17.0	879.0	6.0
07	21.0	53.0	8.0	918.0
08	14.0	9.0	917.0	60.0
09	96.0	66.0	625.0	213.0
10	98.0	463.0	276.0	163.0
11	179.0	286.0	164.0	371.0

PFM

	A	C	G	T
01	0.395	0.256	0.081	0.268
02	0.202	0.291	0.478	0.029
03	0.015	0.967	0.016	0.002
04	0.932	0.012	0.045	0.011
05	0.009	0.944	0.008	0.039
06	0.098	0.017	0.879	0.006
07	0.021	0.053	0.008	0.918
08	0.014	0.009	0.917	0.06
09	0.096	0.066	0.625	0.213
10	0.098	0.463	0.276	0.163
11	0.179	0.286	0.164	0.371

PWM

	A	C	G	T
01	0.455	0.024	-1.113	0.069
02	-0.212	0.151	0.645	-2.103
03	-2.711	1.348	-2.653	-4.213
04	1.311	-2.909	-1.684	-2.985
05	-3.156	1.324	-3.253	-1.821
06	-0.926	-2.598	1.252	-3.484
07	-2.405	-1.526	-3.253	1.296
08	-2.773	-3.156	1.295	-1.406
09	-0.946	-1.313	0.912	-0.159
10	-0.926	0.613	0.098	-0.424
11	-0.331	0.134	-0.418	0.393

Standard thresholds

P-value	Threshold
0.001	4.56159
0.0005	5.440925
0.0001	7.37972