MUSC.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MUSC.H12INVITRO.0.SM.B
Gene (human)	MSC (GeneCards)
Gene synonyms (human)	ABF1, BHLHA22
Gene (mouse)	Msc
Gene synonyms (mouse)	Myor
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	12
Consensus	dvCATATGKTvn
GC content	46.85%
Information content (bits; total / per base)	12.591 / 1.049
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	6729

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.973	0.96	0.909	0.892	0.779	0.78
Overall, 4 experiments	best	0.998	0.996	0.992	0.989	0.963	0.957
Methyl HT-SELEX, 2 experiments	median	0.985	0.978	0.941	0.932	0.854	0.855
Methyl HT-SELEX, 2 experiments	best	0.998	0.996	0.992	0.989	0.963	0.957
Non-Methyl HT-SELEX, 2 experiments	median	0.941	0.919	0.859	0.838	0.746	0.742
Non-Methyl HT-SELEX, 2 experiments	best	0.975	0.962	0.928	0.908	0.815	0.806

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Tal-related {1.2.3} (TFClass)
TF subfamily	MESP {1.2.3.3} (TFClass)
TFClass ID	TFClass: 1.2.3.3.4
HGNC	HGNC:7321
MGI	MGI:1333884
EntrezGene (human)	GeneID:9242 (SSTAR profile)
EntrezGene (mouse)	GeneID:17681 (SSTAR profile)
UniProt ID (human)	MUSC_HUMAN
UniProt ID (mouse)	MUSC_MOUSE
UniProt AC (human)	O60682 (TFClass)
UniProt AC (mouse)	O88940 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	MUSC.H12INVITRO.0.SM.B.pcm
PWM	MUSC.H12INVITRO.0.SM.B.pwm
PFM	MUSC.H12INVITRO.0.SM.B.pfm
Alignment	MUSC.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	MUSC.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	MUSC.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	MUSC.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	MUSC.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	MUSC.H12INVITRO.0.SM.B_homer_format_0.001.txt MUSC.H12INVITRO.0.SM.B_homer_format_0.0005.txt MUSC.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2358.75	870.75	2567.75	931.75
02	2115.5	2979.5	1297.5	336.5
03	189.0	6449.0	80.0	11.0
04	6652.0	2.0	60.0	15.0
05	0.0	2.0	1632.0	5095.0
06	5166.0	1476.0	87.0	0.0
07	40.0	0.0	0.0	6689.0
08	0.0	1.0	6727.0	1.0
09	143.0	104.0	4229.0	2253.0
10	118.0	1206.0	106.0	5299.0
11	1800.75	886.75	3503.75	537.75
12	1624.0	1655.0	1908.0	1542.0

PFM

	A	C	G	T
01	0.351	0.129	0.382	0.138
02	0.314	0.443	0.193	0.05
03	0.028	0.958	0.012	0.002
04	0.989	0.0	0.009	0.002
05	0.0	0.0	0.243	0.757
06	0.768	0.219	0.013	0.0
07	0.006	0.0	0.0	0.994
08	0.0	0.0	1.0	0.0
09	0.021	0.015	0.628	0.335
10	0.018	0.179	0.016	0.787
11	0.268	0.132	0.521	0.08
12	0.241	0.246	0.284	0.229

PWM

	A	C	G	T
01	0.338	-0.657	0.422	-0.59
02	0.229	0.571	-0.259	-1.604
03	-2.176	1.343	-3.02	-4.849
04	1.374	-5.993	-3.299	-4.584
05	-6.639	-5.993	-0.03	1.107
06	1.121	-0.131	-2.938	-6.639
07	-3.687	-6.639	-6.639	1.379
08	-6.639	-6.265	1.385	-6.265
09	-2.451	-2.764	0.921	0.292
10	-2.64	-0.332	-2.745	1.146
11	0.068	-0.639	0.733	-1.138
12	-0.035	-0.016	0.126	-0.087

Standard thresholds

P-value	Threshold
0.001	3.29923
0.0005	4.670475
0.0001	7.396645