MTF1.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MTF1.H12CORE.0.SM.B
Gene (human)	MTF1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mtf1
Gene synonyms (mouse)	Mtf-1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	17
Consensus	nvbRYCGTGTGCAAARv
GC content	54.25%
Information content (bits; total / per base)	21.793 / 1.282
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	6518

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.807	0.82	0.655	0.675	0.586	0.605
Overall, 2 experiments	best	0.83	0.84	0.669	0.688	0.594	0.613
Methyl HT-SELEX, 1 experiments	median	0.83	0.84	0.669	0.688	0.594	0.613
Methyl HT-SELEX, 1 experiments	best	0.83	0.84	0.669	0.688	0.594	0.613
Non-Methyl HT-SELEX, 1 experiments	median	0.784	0.799	0.641	0.661	0.578	0.596
Non-Methyl HT-SELEX, 1 experiments	best	0.784	0.799	0.641	0.661	0.578	0.596

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	MTF1-like {2.3.3.24} (TFClass)
TFClass ID	TFClass: 2.3.3.24.1
HGNC	HGNC:7428
MGI	MGI:101786
EntrezGene (human)	GeneID:4520 (SSTAR profile)
EntrezGene (mouse)	GeneID:17764 (SSTAR profile)
UniProt ID (human)	MTF1_HUMAN
UniProt ID (mouse)	MTF1_MOUSE
UniProt AC (human)	Q14872 (TFClass)
UniProt AC (mouse)	Q07243 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	MTF1.H12CORE.0.SM.B.pcm
PWM	MTF1.H12CORE.0.SM.B.pwm
PFM	MTF1.H12CORE.0.SM.B.pfm
Alignment	MTF1.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	MTF1.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	MTF1.H12CORE.0.SM.B_jaspar_format.txt
MEME format	MTF1.H12CORE.0.SM.B_meme_format.meme
Transfac format	MTF1.H12CORE.0.SM.B_transfac_format.txt
Homer format	MTF1.H12CORE.0.SM.B_homer_format_0.001.txt MTF1.H12CORE.0.SM.B_homer_format_0.0005.txt MTF1.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1947.0	1695.0	1626.0	1250.0
02	2096.25	778.25	2884.25	759.25
03	932.0	1609.0	2936.0	1041.0
04	1582.0	206.0	4229.0	501.0
05	654.0	4958.0	184.0	722.0
06	14.0	5863.0	636.0	5.0
07	5.0	9.0	6492.0	12.0
08	5.0	4.0	17.0	6492.0
09	0.0	0.0	6490.0	28.0
10	0.0	2.0	17.0	6499.0
11	0.0	0.0	6517.0	1.0
12	5.0	6508.0	4.0	1.0
13	6506.0	1.0	10.0	1.0
14	6411.0	43.0	33.0	31.0
15	6431.0	52.0	19.0	16.0
16	4279.25	312.25	1647.25	279.25
17	1387.0	1645.0	2684.0	802.0

PFM

	A	C	G	T
01	0.299	0.26	0.249	0.192
02	0.322	0.119	0.443	0.116
03	0.143	0.247	0.45	0.16
04	0.243	0.032	0.649	0.077
05	0.1	0.761	0.028	0.111
06	0.002	0.9	0.098	0.001
07	0.001	0.001	0.996	0.002
08	0.001	0.001	0.003	0.996
09	0.0	0.0	0.996	0.004
10	0.0	0.0	0.003	0.997
11	0.0	0.0	1.0	0.0
12	0.001	0.998	0.001	0.0
13	0.998	0.0	0.002	0.0
14	0.984	0.007	0.005	0.005
15	0.987	0.008	0.003	0.002
16	0.657	0.048	0.253	0.043
17	0.213	0.252	0.412	0.123

PWM

	A	C	G	T
01	0.178	0.039	-0.002	-0.265
02	0.252	-0.738	0.57	-0.762
03	-0.558	-0.013	0.588	-0.447
04	-0.03	-2.059	0.953	-1.176
05	-0.911	1.112	-2.171	-0.812
06	-4.613	1.279	-0.939	-5.424
07	-5.424	-4.982	1.381	-4.744
08	-5.424	-5.574	-4.443	1.381
09	-6.611	-6.611	1.381	-3.99
10	-6.611	-5.963	-4.443	1.382
11	-6.611	-6.611	1.385	-6.236
12	-5.424	1.384	-5.574	-6.236
13	1.383	-6.236	-4.896	-6.236
14	1.369	-3.586	-3.836	-3.895
15	1.372	-3.405	-4.344	-4.496
16	0.965	-1.647	0.011	-1.757
17	-0.161	0.009	0.499	-0.708

Standard thresholds

P-value	Threshold
0.001	-5.29379
0.0005	-3.20109
0.0001	1.15041