MotifMSX2.H12INVIVO.0.SM.D
Gene (human)MSX2
(GeneCards)
Gene synonyms (human)HOX8
Gene (mouse)Msx2
Gene synonyms (mouse)Hox-8.1, Msx-2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length9
ConsensusnvYAATTAn
GC content29.38%
Information content (bits; total / per base)10.08 / 1.12
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words2301

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.873 0.861 0.803 0.799 0.763 0.761
best 0.989 0.982 0.983 0.972 0.974 0.96
Methyl HT-SELEX, 1 experiments median 0.982 0.971 0.974 0.958 0.961 0.94
best 0.982 0.971 0.974 0.958 0.961 0.94
Non-Methyl HT-SELEX, 3 experiments median 0.764 0.751 0.632 0.64 0.566 0.582
best 0.989 0.982 0.983 0.972 0.974 0.96

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.649 0.052 0.526 0.32
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyMSX {3.1.2.11} (TFClass)
TFClass IDTFClass: 3.1.2.11.2
HGNCHGNC:7392
MGIMGI:97169
EntrezGene (human)GeneID:4488
(SSTAR profile)
EntrezGene (mouse)GeneID:17702
(SSTAR profile)
UniProt ID (human)MSX2_HUMAN
UniProt ID (mouse)MSX2_MOUSE
UniProt AC (human)P35548
(TFClass)
UniProt AC (mouse)Q03358
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01666.25667.25558.25409.25
02274.251147.25695.25184.25
0367.01390.0167.0677.0
042295.03.03.00.0
052283.017.01.00.0
060.022.00.02279.0
070.09.087.02205.0
082122.7560.75109.757.75
09773.75563.75583.75379.75
PFM
ACGT
010.290.290.2430.178
020.1190.4990.3020.08
030.0290.6040.0730.294
040.9970.0010.0010.0
050.9920.0070.00.0
060.00.010.00.99
070.00.0040.0380.958
080.9230.0260.0480.003
090.3360.2450.2540.165
PWM
ACGT
010.1460.148-0.03-0.339
02-0.7370.6890.189-1.131
03-2.1250.88-1.2290.162
041.381-4.762-4.762-5.698
051.376-3.417-5.281-5.698
06-5.698-3.183-5.6981.374
07-5.698-3.966-1.871.341
081.303-2.22-1.642-4.088
090.296-0.020.015-0.414
Standard thresholds
P-value Threshold
0.001 4.72153
0.0005 5.889515
0.0001 7.80014