| Motif | MSX2.H12INVITRO.0.SM.B |
| Gene (human) | MSX2 (GeneCards) |
| Gene synonyms (human) | HOX8 |
| Gene (mouse) | Msx2 |
| Gene synonyms (mouse) | Hox-8.1, Msx-2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | B |
| Motif | MSX2.H12INVITRO.0.SM.B |
| Gene (human) | MSX2 (GeneCards) |
| Gene synonyms (human) | HOX8 |
| Gene (mouse) | Msx2 |
| Gene synonyms (mouse) | Hox-8.1, Msx-2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | B |
| Motif length | 9 |
| Consensus | nbYAATTMn |
| GC content | 32.45% |
| Information content (bits; total / per base) | 8.498 / 0.944 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8213 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.873 | 0.864 | 0.803 | 0.8 | 0.764 | 0.762 |
| best | 0.992 | 0.989 | 0.984 | 0.975 | 0.975 | 0.962 | |
| Methyl HT-SELEX, 1 experiments | median | 0.984 | 0.977 | 0.975 | 0.961 | 0.962 | 0.942 |
| best | 0.984 | 0.977 | 0.975 | 0.961 | 0.962 | 0.942 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.761 | 0.751 | 0.632 | 0.639 | 0.566 | 0.582 |
| best | 0.992 | 0.989 | 0.984 | 0.975 | 0.975 | 0.962 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.612 | 0.054 | 0.427 | 0.229 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | NK-related {3.1.2} (TFClass) |
| TF subfamily | MSX {3.1.2.11} (TFClass) |
| TFClass ID | TFClass: 3.1.2.11.2 |
| HGNC | HGNC:7392 |
| MGI | MGI:97169 |
| EntrezGene (human) | GeneID:4488 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17702 (SSTAR profile) |
| UniProt ID (human) | MSX2_HUMAN |
| UniProt ID (mouse) | MSX2_MOUSE |
| UniProt AC (human) | P35548 (TFClass) |
| UniProt AC (mouse) | Q03358 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | MSX2.H12INVITRO.0.SM.B.pcm |
| PWM | MSX2.H12INVITRO.0.SM.B.pwm |
| PFM | MSX2.H12INVITRO.0.SM.B.pfm |
| Alignment | MSX2.H12INVITRO.0.SM.B.words.tsv |
| Threshold to P-value map | MSX2.H12INVITRO.0.SM.B.thr |
| Motif in other formats | |
| JASPAR format | MSX2.H12INVITRO.0.SM.B_jaspar_format.txt |
| MEME format | MSX2.H12INVITRO.0.SM.B_meme_format.meme |
| Transfac format | MSX2.H12INVITRO.0.SM.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2394.5 | 2355.5 | 2133.5 | 1329.5 |
| 02 | 933.75 | 4056.75 | 2279.75 | 942.75 |
| 03 | 0.0 | 4887.0 | 682.0 | 2644.0 |
| 04 | 8184.0 | 0.0 | 0.0 | 29.0 |
| 05 | 7983.0 | 230.0 | 0.0 | 0.0 |
| 06 | 0.0 | 156.0 | 1.0 | 8056.0 |
| 07 | 6.0 | 481.0 | 791.0 | 6935.0 |
| 08 | 5584.75 | 1052.75 | 681.75 | 893.75 |
| 09 | 2197.0 | 2117.0 | 2079.0 | 1820.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.292 | 0.287 | 0.26 | 0.162 |
| 02 | 0.114 | 0.494 | 0.278 | 0.115 |
| 03 | 0.0 | 0.595 | 0.083 | 0.322 |
| 04 | 0.996 | 0.0 | 0.0 | 0.004 |
| 05 | 0.972 | 0.028 | 0.0 | 0.0 |
| 06 | 0.0 | 0.019 | 0.0 | 0.981 |
| 07 | 0.001 | 0.059 | 0.096 | 0.844 |
| 08 | 0.68 | 0.128 | 0.083 | 0.109 |
| 09 | 0.268 | 0.258 | 0.253 | 0.222 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.154 | 0.137 | 0.038 | -0.434 |
| 02 | -0.787 | 0.68 | 0.105 | -0.777 |
| 03 | -6.816 | 0.867 | -1.1 | 0.253 |
| 04 | 1.382 | -6.816 | -6.816 | -4.186 |
| 05 | 1.357 | -2.18 | -6.816 | -6.816 |
| 06 | -6.816 | -2.564 | -6.449 | 1.366 |
| 07 | -5.518 | -1.448 | -0.952 | 1.216 |
| 08 | 1.0 | -0.667 | -1.1 | -0.83 |
| 09 | 0.068 | 0.031 | 0.012 | -0.12 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.363215 |
| 0.0005 | 5.972635 |
| 0.0001 | 7.40281 |