MotifMSX2.H12CORE.1.SM.B
Gene (human)MSX2
(GeneCards)
Gene synonyms (human)HOX8
Gene (mouse)Msx2
Gene synonyms (mouse)Hox-8.1, Msx-2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length20
ConsensusbhhWWddnnnSTAATTASbv
GC content34.61%
Information content (bits; total / per base)14.269 / 0.713
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words556

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.868 0.863 0.795 0.796 0.755 0.756
best 0.989 0.982 0.982 0.971 0.971 0.956
Methyl HT-SELEX, 1 experiments median 0.984 0.974 0.973 0.958 0.957 0.937
best 0.984 0.974 0.973 0.958 0.957 0.937
Non-Methyl HT-SELEX, 3 experiments median 0.752 0.751 0.617 0.633 0.553 0.576
best 0.989 0.982 0.982 0.971 0.971 0.956

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.584 0.051 0.427 0.264
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyMSX {3.1.2.11} (TFClass)
TFClass IDTFClass: 3.1.2.11.2
HGNCHGNC:7392
MGIMGI:97169
EntrezGene (human)GeneID:4488
(SSTAR profile)
EntrezGene (mouse)GeneID:17702
(SSTAR profile)
UniProt ID (human)MSX2_HUMAN
UniProt ID (mouse)MSX2_MOUSE
UniProt AC (human)P35548
(TFClass)
UniProt AC (mouse)Q03358
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0190.0241.0106.0119.0
02304.5117.552.581.5
03355.073.055.073.0
04148.046.032.0330.0
05118.040.037.0361.0
06301.047.070.0138.0
07213.086.0109.0148.0
08156.0112.0115.0173.0
09187.0133.0110.0126.0
10162.0128.0189.077.0
1139.0328.0108.081.0
120.0208.00.0348.0
13556.00.00.00.0
14556.00.00.00.0
150.00.00.0556.0
160.00.00.0556.0
17491.00.065.00.0
1863.0167.0303.023.0
1952.0226.0169.0109.0
2095.25143.25232.2585.25
PFM
ACGT
010.1620.4330.1910.214
020.5480.2110.0940.147
030.6380.1310.0990.131
040.2660.0830.0580.594
050.2120.0720.0670.649
060.5410.0850.1260.248
070.3830.1550.1960.266
080.2810.2010.2070.311
090.3360.2390.1980.227
100.2910.230.340.138
110.070.590.1940.146
120.00.3740.00.626
131.00.00.00.0
141.00.00.00.0
150.00.00.01.0
160.00.00.01.0
170.8830.00.1170.0
180.1130.30.5450.041
190.0940.4060.3040.196
200.1710.2580.4180.153
PWM
ACGT
01-0.4290.546-0.268-0.153
020.778-0.166-0.955-0.526
030.931-0.634-0.91-0.634
040.062-1.083-1.4320.858
05-0.162-1.218-1.2930.947
060.767-1.063-0.675-0.007
070.423-0.473-0.240.062
080.114-0.213-0.1870.217
090.294-0.044-0.231-0.097
100.152-0.0810.304-0.582
11-1.2420.852-0.249-0.532
12-4.4880.399-4.4880.911
131.378-4.488-4.488-4.488
141.378-4.488-4.488-4.488
15-4.488-4.488-4.4881.378
16-4.488-4.488-4.4881.378
171.254-4.488-0.747-4.488
18-0.7780.1820.773-1.744
19-0.9650.4820.193-0.24
20-0.3730.030.509-0.482
Standard thresholds
P-value Threshold
0.001 2.88096
0.0005 4.24216
0.0001 7.01061