MotifMSX1.H12INVIVO.0.SM.D
Gene (human)MSX1
(GeneCards)
Gene synonyms (human)HOX7
Gene (mouse)Msx1
Gene synonyms (mouse)Hox7, Hox7.1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length11
ConsensusnvYAATTAvbn
GC content33.79%
Information content (bits; total / per base)11.505 / 1.046
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words8860

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.869 0.821 0.74 0.718 0.633 0.638
best 0.982 0.973 0.935 0.919 0.847 0.823
Methyl HT-SELEX, 2 experiments median 0.898 0.862 0.822 0.797 0.728 0.72
best 0.957 0.929 0.935 0.902 0.847 0.823
Non-Methyl HT-SELEX, 6 experiments median 0.869 0.821 0.74 0.718 0.633 0.638
best 0.982 0.973 0.933 0.919 0.843 0.82

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.855 0.57 0.791 0.594
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyMSX {3.1.2.11} (TFClass)
TFClass IDTFClass: 3.1.2.11.1
HGNCHGNC:7391
MGIMGI:97168
EntrezGene (human)GeneID:4487
(SSTAR profile)
EntrezGene (mouse)GeneID:17701
(SSTAR profile)
UniProt ID (human)MSX1_HUMAN
UniProt ID (mouse)MSX1_MOUSE
UniProt AC (human)P28360
(TFClass)
UniProt AC (mouse)P13297
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012484.252446.252044.251885.25
021186.253256.253240.251177.25
0344.05159.08.03649.0
048858.02.00.00.0
058860.00.00.00.0
060.00.00.08860.0
070.00.00.08860.0
088854.00.06.00.0
092583.02498.03038.0741.0
10744.54151.52208.51755.5
112012.252289.252581.251977.25
PFM
ACGT
010.280.2760.2310.213
020.1340.3680.3660.133
030.0050.5820.0010.412
041.00.00.00.0
051.00.00.00.0
060.00.00.01.0
070.00.00.01.0
080.9990.00.0010.0
090.2920.2820.3430.084
100.0840.4690.2490.198
110.2270.2580.2910.223
PWM
ACGT
010.1150.099-0.08-0.161
02-0.6240.3850.38-0.631
03-3.8690.845-5.3750.499
041.385-6.252-6.883-6.883
051.386-6.883-6.883-6.883
06-6.883-6.883-6.8831.386
07-6.883-6.883-6.8831.386
081.385-6.883-5.591-6.883
090.1540.120.316-1.093
10-1.0880.628-0.003-0.232
11-0.0960.0330.153-0.113
Standard thresholds
P-value Threshold
0.001 1.04991
0.0005 4.21101
0.0001 8.04351