MotifMSX1.H12INVITRO.1.S.C
Gene (human)MSX1
(GeneCards)
Gene synonyms (human)HOX7
Gene (mouse)Msx1
Gene synonyms (mouse)Hox7, Hox7.1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length22
ConsensusnnvbYAATTAvnnnnhWWWWdn
GC content31.32%
Information content (bits; total / per base)14.17 / 0.644
Data sourcesHT-SELEX
Aligned words8743

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.874 0.84 0.734 0.722 0.625 0.637
best 0.994 0.992 0.936 0.932 0.825 0.797
Methyl HT-SELEX, 2 experiments median 0.892 0.854 0.808 0.782 0.712 0.706
best 0.939 0.897 0.915 0.872 0.823 0.795
Non-Methyl HT-SELEX, 6 experiments median 0.874 0.84 0.734 0.722 0.625 0.637
best 0.994 0.992 0.936 0.932 0.825 0.797

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.735 0.435 0.705 0.532
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyMSX {3.1.2.11} (TFClass)
TFClass IDTFClass: 3.1.2.11.1
HGNCHGNC:7391
MGIMGI:97168
EntrezGene (human)GeneID:4487
(SSTAR profile)
EntrezGene (mouse)GeneID:17701
(SSTAR profile)
UniProt ID (human)MSX1_HUMAN
UniProt ID (mouse)MSX1_MOUSE
UniProt AC (human)P28360
(TFClass)
UniProt AC (mouse)P13297
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
012926.751427.751898.752489.75
022674.51911.52712.51444.5
033533.01613.02349.01248.0
04841.03733.03138.01031.0
0514.05179.019.03531.0
068699.017.026.01.0
078742.00.01.00.0
080.00.00.08743.0
090.022.01.08720.0
108411.02.0325.05.0
113310.01628.03004.0801.0
121973.02887.01856.02027.0
132556.01716.02188.02283.0
143125.02124.01693.01801.0
152026.02903.01805.02009.0
162075.03169.0742.02757.0
175329.0976.0705.01733.0
185401.0625.0482.02235.0
192045.0508.0471.05719.0
202412.0552.0580.05199.0
214851.5708.51012.52170.5
222890.01589.01950.02314.0
PFM
ACGT
010.3350.1630.2170.285
020.3060.2190.310.165
030.4040.1840.2690.143
040.0960.4270.3590.118
050.0020.5920.0020.404
060.9950.0020.0030.0
071.00.00.00.0
080.00.00.01.0
090.00.0030.00.997
100.9620.00.0370.001
110.3790.1860.3440.092
120.2260.330.2120.232
130.2920.1960.250.261
140.3570.2430.1940.206
150.2320.3320.2060.23
160.2370.3620.0850.315
170.610.1120.0810.198
180.6180.0710.0550.256
190.2340.0580.0540.654
200.2760.0630.0660.595
210.5550.0810.1160.248
220.3310.1820.2230.265
PWM
ACGT
010.292-0.425-0.1410.13
020.202-0.1340.216-0.414
030.48-0.3030.072-0.56
04-0.9530.5350.361-0.75
05-4.9010.862-4.6340.479
061.38-4.732-4.349-6.506
071.385-6.871-6.506-6.871
08-6.871-6.871-6.8711.386
09-6.871-4.502-6.5061.383
101.347-6.239-1.9-5.707
110.415-0.2940.318-1.002
12-0.1020.278-0.163-0.075
130.156-0.2420.0010.043
140.357-0.029-0.255-0.193
15-0.0760.284-0.191-0.084
16-0.0520.371-1.0780.232
170.891-0.805-1.129-0.232
180.904-1.249-1.5080.022
19-0.066-1.456-1.5310.961
200.098-1.373-1.3240.866
210.797-1.124-0.768-0.007
220.279-0.318-0.1140.057
Standard thresholds
P-value Threshold
0.001 1.89971
0.0005 3.62356
0.0001 6.94061